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Showing 1 - 6 of 6 results

Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)



MKC-1 is an orally available cell cycle inhibitor with downstream targets that include tubulin and the importin-β family. MKC-1 has shown broad antitumor activity in preclinical models. MKC-1 and its metabolites inhibit tubulin polymerization, blocki...
PD 173074 is a potent ATP-competitive inhibitor of fibroblast growth factor receptor 1 and 3. PD173074 is also an effective inhibitor of FGFR2, FGFR4, and VEGFR2. Compared to FGFR1, PD173074 weakly inhibits the activities of Src, InsR, EGFR, PDGFR, M...
Status:
US Approved Rx (1996)
First approved in 1996

Class:
POLYMER



Pentosan polysulfate sodium (brand name ELMIRON) is a low molecular weight heparin-like compound. It has anticoagulant and fibrinolytic effects and is indicated for the relief of bladder pain or discomfort associated with interstitial cystitis. The m...
Status:
US Approved Rx (1996)
First approved in 1996

Class:
POLYMER



Pentosan polysulfate sodium (brand name ELMIRON) is a low molecular weight heparin-like compound. It has anticoagulant and fibrinolytic effects and is indicated for the relief of bladder pain or discomfort associated with interstitial cystitis. The m...