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Primary Target

Complement factor B

3

Histamine H1 receptor

315

Dopamine D2 receptor

297

DNA

278

Bacterial penicillin-binding protein

233

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Development Status

US Previously Marketed

3

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Highest Phase

Approved

3

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Approval Year

1954

3

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Condition

Hepatobiliary disease

3

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Treatment Modality

Diagnostic

3

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CNS Activity

CNS Penetrant

3

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Originator

Langecker, H.|Harwart, A.|Junkmann, K.

3

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Substance Class

Chemical

3

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Code System

CAS

3

ChEMBL

3

DRUG BANK

3

ECHA (EC/EINECS)

3

EPA CompTox

3

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ATC Level 1

VARIOUS

1

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ATC Level 2

CONTRAST MEDIA

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ATC Level 3

X-RAY CONTRAST MEDIA, IODINATED

1

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ATC Level 4

Watersoluble, hepatotropic X-ray contrast media

1

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Substance Form

Salts, Hydrates, Esters, etc.

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Principal Form

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Showing 1 - 3 of 3 results

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IODIPAMIDE

TKQ858A3VW

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Status:

US Previously Marketed

First approved in 1954

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Complement factor B

Cholesteryl ester transfer protein

Complement factor B

Conditions:

Hepatobiliary disease

Iodipamide is used as a contrast agent for cholecystography and intravenous cholangiography. Following intravenous administration of Cholografin Meglumine, iodipamide is carried to the liver where it is rapidly secreted. The contrast medium appears i...

n the bile within 10 to 15 minutes after injection, thus permitting visualization of the hepatic and common bile ducts, even in cholecystectomized patients. Iodipamide (Cholografin Meglumine) is indicated for intravenous cholangiography and cholecystography as follows: (a) visualization of the gallbladder and biliary ducts in the differential diagnosis of acute abdominal conditions, (b) visualization of the biliary ducts, especially in patients with symptoms after cholecystectomy, and (c) visualization of the gallbladder in patients unable to take oral contrast media or to absorb contrast media from the gastrointestinal tract. The biliary ducts are readily visualized within about 25 minutes after administration, except in patients with impaired liver function. The gallbladder begins to fill within an hour after injection; maximum filling is reached after two to two and one-half hours. Organic iodine compounds block x-rays as they pass through the body, thereby allowing body structures containing iodine to be delineated in contrast to those structures that do not contain iodine. The degree of opacity produced by these iodinated organic compounds is directly proportional to the total amount (concentration and volume) of the iodinated contrast agent in the path of the x-rays. Iodipamide's primary excretion through the hepato-biliary system and concentration in bile allows visualization of the gallbladder and biliary ducts.

IODIPAMIDE SODIUM

3J6WZA9PXS

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Status:

US Previously Marketed

First approved in 1954

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Complement factor B

Cholesteryl ester transfer protein

Complement factor B

Conditions:

Hepatobiliary disease

Iodipamide is used as a contrast agent for cholecystography and intravenous cholangiography. Following intravenous administration of Cholografin Meglumine, iodipamide is carried to the liver where it is rapidly secreted. The contrast medium appears i...

n the bile within 10 to 15 minutes after injection, thus permitting visualization of the hepatic and common bile ducts, even in cholecystectomized patients. Iodipamide (Cholografin Meglumine) is indicated for intravenous cholangiography and cholecystography as follows: (a) visualization of the gallbladder and biliary ducts in the differential diagnosis of acute abdominal conditions, (b) visualization of the biliary ducts, especially in patients with symptoms after cholecystectomy, and (c) visualization of the gallbladder in patients unable to take oral contrast media or to absorb contrast media from the gastrointestinal tract. The biliary ducts are readily visualized within about 25 minutes after administration, except in patients with impaired liver function. The gallbladder begins to fill within an hour after injection; maximum filling is reached after two to two and one-half hours. Organic iodine compounds block x-rays as they pass through the body, thereby allowing body structures containing iodine to be delineated in contrast to those structures that do not contain iodine. The degree of opacity produced by these iodinated organic compounds is directly proportional to the total amount (concentration and volume) of the iodinated contrast agent in the path of the x-rays. Iodipamide's primary excretion through the hepato-biliary system and concentration in bile allows visualization of the gallbladder and biliary ducts.

IODIPAMIDE MEGLUMINE

X064O0Y1A4

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Search for Structure

Status:

US Previously Marketed

First approved in 1954

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Complement factor B

Cholesteryl ester transfer protein

Complement factor B

Conditions:

Hepatobiliary disease

Iodipamide is used as a contrast agent for cholecystography and intravenous cholangiography. Following intravenous administration of Cholografin Meglumine, iodipamide is carried to the liver where it is rapidly secreted. The contrast medium appears i...

n the bile within 10 to 15 minutes after injection, thus permitting visualization of the hepatic and common bile ducts, even in cholecystectomized patients. Iodipamide (Cholografin Meglumine) is indicated for intravenous cholangiography and cholecystography as follows: (a) visualization of the gallbladder and biliary ducts in the differential diagnosis of acute abdominal conditions, (b) visualization of the biliary ducts, especially in patients with symptoms after cholecystectomy, and (c) visualization of the gallbladder in patients unable to take oral contrast media or to absorb contrast media from the gastrointestinal tract. The biliary ducts are readily visualized within about 25 minutes after administration, except in patients with impaired liver function. The gallbladder begins to fill within an hour after injection; maximum filling is reached after two to two and one-half hours. Organic iodine compounds block x-rays as they pass through the body, thereby allowing body structures containing iodine to be delineated in contrast to those structures that do not contain iodine. The degree of opacity produced by these iodinated organic compounds is directly proportional to the total amount (concentration and volume) of the iodinated contrast agent in the path of the x-rays. Iodipamide's primary excretion through the hepato-biliary system and concentration in bile allows visualization of the gallbladder and biliary ducts.

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