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National Institutes of Health
NCATS
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Development Status
Other
177
US Approved Rx
177
Possibly Marketed Outside US
137
US Previously Marketed
103
Investigational
54
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Primary Target
Cytochrome P450 3A4
54
Cytochrome P450 1A2
33
Cytochrome P450 2D6
30
Steryl-sulfatase
30
Androgen Receptor
29
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Highest Phase
Approved
330
Phase II
32
Not Provided
26
Phase III
20
Phase I
4
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Approval Year
Unknown
297
1921
56
1940
35
1971
18
1985
16
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Condition
Unknown
158
Postmenopausal osteoporosis
27
Primary ovarian failure
27
Vaginal atrophy
27
Burn
24
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Treatment Modality
Primary
345
Preventing
112
Palliative
71
Curative
69
Diagnostic
60
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CNS Activity
CNS Penetrant
158
CNS Active
145
CNS Non-penetrant
42
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Originator
Schering Kahlbaum
27
Orisheva, R.M.|Nechepurenko, Yu.V.|Sokolov, V.G.
16
Sigma-Tau
13
Merck
12
Eijkman, C.
11
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Substance Class
Chemical
650
Mixture
9
Protein
2
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INN Stem
Chemical substance(-ine)
4
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Code System
FDA UNII
661
CAS
651
PUBCHEM
643
EPA CompTox
548
SMS_ID
339
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ATC Level 1
ALIMENTARY TRACT AND METABOLISM
17
CARDIOVASCULAR SYSTEM
12
DERMATOLOGICALS
12
SENSORY ORGANS
12
VARIOUS
12
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ATC Level 2
OPHTHALMOLOGICALS
12
ALL OTHER THERAPEUTIC PRODUCTS
6
DIAGNOSTIC AGENTS
6
CARDIAC THERAPY
5
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
5
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ATC Level 3
ALL OTHER THERAPEUTIC PRODUCTS
6
OTHER DIAGNOSTIC AGENTS
6
ANTIINFECTIVES
5
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
5
ANTIGLAUCOMA PREPARATIONS AND MIOTICS
4
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ATC Level 4
Antidotes
4
Nucleosides and nucleotides excl. reverse transcriptase inhibitors
3
Other cardiac preparations
3
Other dermatologicals
3
Other nervous system drugs
3
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Substance Form
Salts, Hydrates, Esters, etc.
351
Principal Form
310
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Pharmacology
Substrate
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ANGIOTENSIN I ACETATE
MORE DETAILS
A4M6Y4755P
Subunit
1
(10) Similarity Search
Export Data
Sequence Search
Subunit
1
(10) Similarity Search
Status:
Other
Class:
PROTEIN
Targets:
Angiotensin-converting enzyme
94
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