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Development Status

Investigational

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Primary Target

Bacterial DNA gyrase

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Highest Phase

Not Provided

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Approval Year

Unknown

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Condition

Bacterial infections

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Treatment Modality

Curative

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Originator

Bristol-Banyu Research Institute

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Substance Class

Chemical

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Code System

CAS

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ChEMBL

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FDA UNII

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NCI_THESAURUS

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PUBCHEM

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Substance Form

Principal Form

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Salts, Hydrates, Esters, etc.

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COUMERMYCIN

PCH9QZ1IIH

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Status:

Investigational

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Bacterial DNA gyrase

Conditions:

Bacterial infections

Coumermycin is from the aminocoumarin class of antibiotic compounds which acts by inhibiting DNA gyrase. Coumermycin is effective against gram-positive bacteria, but not gram-negative bacteria. Coumermycin its derivatives have been studied since th...

e 1950's as potential antibiotic. However, it has seen little to no clinical development because of its low water solubility, toxicity profile, and ineffectiveness against gram-negative bacteria.

COUMERMYCIN SODIUM

1VHT58TJ83

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Status:

Investigational

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Bacterial DNA gyrase

Conditions:

Bacterial infections

Coumermycin is from the aminocoumarin class of antibiotic compounds which acts by inhibiting DNA gyrase. Coumermycin is effective against gram-positive bacteria, but not gram-negative bacteria. Coumermycin its derivatives have been studied since th...

e 1950's as potential antibiotic. However, it has seen little to no clinical development because of its low water solubility, toxicity profile, and ineffectiveness against gram-negative bacteria.

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