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Showing 1 - 1 of 1 results
Status:
Investigational
Source:
NCT01590277: Phase 1 Interventional Completed Active Ethanol and Active Iomazenil
(2012)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Iomazenil (also known as Ro16-0154, benzodine) is a partial inverse agonist of central-type benzodiazepine receptors (BZR) which binds specifically to BZR with high affinity and a potential treatment for alcohol abuse. The compound was introduced in 1989 by pharmaceutical company Hoffmann-La Roche as an Iodine-123-labelled SPECT tracer for imaging benzodiazepine receptors (GABAA receptors) in the brain.