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Showing 1 - 2 of 2 results

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TALAZOPARIB

9QHX048FRV

Search for Structure

Status:

US Approved Rx (2024)

Source:

NDA217439

(2024)

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=217439

First approved in 2018

Source:

TALZENNA by PFIZER

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=211651

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Poly [ADP-ribose] polymerase 2

Poly [ADP-ribose] polymerase-1

Conditions:

BMN-673 (8R,9S) is the (8R,9S) enantiomer of BMN-673, known as talazoparib. BMN 673 is a novel inhibitor of nuclear enzyme poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity.

TALAZOPARIB TOSYLATE

02WK9U5NZC

Search for Structure

Status:

US Approved Rx (2024)

Source:

NDA217439

(2024)

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=217439

First approved in 2018

Source:

TALZENNA by PFIZER

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=211651

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Poly [ADP-ribose] polymerase 2

Poly [ADP-ribose] polymerase-1

Conditions:

BMN-673 (8R,9S) is the (8R,9S) enantiomer of BMN-673, known as talazoparib. BMN 673 is a novel inhibitor of nuclear enzyme poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity.

Structure of TALAZOPARIB

ABSOLUTE

Structure of TALAZOPARIB TOSYLATE

ABSOLUTE

TALAZOPARIB TOSYLATE

HHS VULNERABILITY DISCLOSURE

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