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US Previously Marketed

4

Possibly Marketed Outside US

2

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Primary Target

Sodium channel alpha subunits; brain (Types I, II, III)

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Highest Phase

Not Provided

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Approval Year

1948

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Unknown

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Condition

Local anesthetic

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Pain

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Primary

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Palliative

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Oradent Chemical

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EPA CompTox

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PUBCHEM

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Showing 1 - 6 of 6 results

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CYCLOMETHYCAINE

15E9I74NZ8

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Status:

US Previously Marketed

First approved in 1948

Class (Stereo):

CHEMICAL (RACEMIC)

Conditions:

Local anesthetic

Cyclomethycaine (also known as Surfacaine) is a local anesthetic.

MEPRYLCAINE

82YT7WU9PW

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Status:

Possibly Marketed Outside US

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Sodium channel alpha subunits; brain (Types I, II, III)

Conditions:

Meprylcaine (also known as Epirocaine and Oracaine) is a local anesthetic with stimulant properties that is structurally related to dimethocaine. Meprylcaine has a relatively potent inhibitory action on the monoamine transporter and inhibits the reup...

take of dopamine, norepinephrine and serotonin. Oracaine is commonly used as the hydrochloride salt and is compatible with the known vasoconstrictors. It has a slightly more rapid onset than procaine with a slight increase in potency. The earliest symptoms of a toxic overdose are stimulation to the central nervous system, thus following the same symptoms as procaine. Not more than 400 mg. (20 ml. of a 2 per cent solution) should be used at any one time for the ambulatory patient. Oracaine, like metycaine, may be used for patients sensitive to the para-aminobenzoic acid derivatives. Oracaine hydrochloride is used at present mainly by the dental profession and in dermatologic surgery.

CYCLOMETHYCAINE SULFATE

02V8D6C69F

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Status:

US Previously Marketed

First approved in 1948

Class (Stereo):

CHEMICAL (RACEMIC)

Conditions:

Local anesthetic

Cyclomethycaine (also known as Surfacaine) is a local anesthetic.

CYCLOMETHYCAINE BISULFATE

7323N7T136

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Status:

US Previously Marketed

First approved in 1948

Class (Stereo):

CHEMICAL (RACEMIC)

Conditions:

Local anesthetic

Cyclomethycaine (also known as Surfacaine) is a local anesthetic.

CYCLOMETHYCAINE HYDROCHLORIDE

2FYK6V755H

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Status:

US Previously Marketed

First approved in 1948

Class (Stereo):

CHEMICAL (RACEMIC)

Conditions:

Local anesthetic

Cyclomethycaine (also known as Surfacaine) is a local anesthetic.

MEPRYLCAINE HYDROCHLORIDE

VR843X5GXG

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Status:

Possibly Marketed Outside US

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Sodium channel alpha subunits; brain (Types I, II, III)

Conditions:

Meprylcaine (also known as Epirocaine and Oracaine) is a local anesthetic with stimulant properties that is structurally related to dimethocaine. Meprylcaine has a relatively potent inhibitory action on the monoamine transporter and inhibits the reup...

take of dopamine, norepinephrine and serotonin. Oracaine is commonly used as the hydrochloride salt and is compatible with the known vasoconstrictors. It has a slightly more rapid onset than procaine with a slight increase in potency. The earliest symptoms of a toxic overdose are stimulation to the central nervous system, thus following the same symptoms as procaine. Not more than 400 mg. (20 ml. of a 2 per cent solution) should be used at any one time for the ambulatory patient. Oracaine, like metycaine, may be used for patients sensitive to the para-aminobenzoic acid derivatives. Oracaine hydrochloride is used at present mainly by the dental profession and in dermatologic surgery.

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