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Designated

3

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Primary Target

Protein methylesterase (rat)

3

Thrombokinase (Bos taurus)

3

Trypsin

3

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Approval Year

Unknown

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Condition

Gingivitis

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Myocardial stunning

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Skin cancer

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Preventing

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Primary

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CNS Activity

CNS Active

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Aoyagi, T. et al.

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Chemical

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CAS

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FDA UNII

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PUBCHEM

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CHEBI

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EPA CompTox

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Salts, Hydrates, Esters, etc.

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Showing 1 - 3 of 3 results

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LEUPEPTIN

J97339NR3V

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Status:

Designated

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Protein methylesterase (rat)

Thrombokinase (Bos taurus)

Conditions:

Myocardial stunning

Leupeptin is produced by various species of Actinomycetes. It strongly inhibits proteolysis by plasmin, trypsin and papin. Leupeptin is well absorbed through oral route. Leupeptin has been known to cause various neuropathological changes in vivo rese...

mbling those of aging or neurodegenerative processes in the human brain, including the accumulation of neuronal processes and neuronal cytoskeletal abnormalities leading to neurofibrillary tangle (NFT)-like formations. In in vitro experiments, leupeptin protects the heart from myocardial stunning. Leupeptin was found to inhibit tumorigenesis in mouse skin induced by a single, noncarcinogenic dose of 7,12- dimethylbenz(a)anthracene followed by repeated application of croton oil. Tumors that had already been induced were scarcely affected by leupeptin.

LEUPEPTIN HEMISULFATE ANHYDROUS

05V9Y5208M

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Search for Structure

Status:

Designated

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Protein methylesterase (rat)

Thrombokinase (Bos taurus)

Conditions:

Myocardial stunning

Leupeptin is produced by various species of Actinomycetes. It strongly inhibits proteolysis by plasmin, trypsin and papin. Leupeptin is well absorbed through oral route. Leupeptin has been known to cause various neuropathological changes in vivo rese...

mbling those of aging or neurodegenerative processes in the human brain, including the accumulation of neuronal processes and neuronal cytoskeletal abnormalities leading to neurofibrillary tangle (NFT)-like formations. In in vitro experiments, leupeptin protects the heart from myocardial stunning. Leupeptin was found to inhibit tumorigenesis in mouse skin induced by a single, noncarcinogenic dose of 7,12- dimethylbenz(a)anthracene followed by repeated application of croton oil. Tumors that had already been induced were scarcely affected by leupeptin.

LEUPEPTIN HEMISULFATE MONOHYDRATE

P4TZ8HY7S7

Export Data
Search for Structure

Status:

Designated

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Protein methylesterase (rat)

Thrombokinase (Bos taurus)

Conditions:

Myocardial stunning

Leupeptin is produced by various species of Actinomycetes. It strongly inhibits proteolysis by plasmin, trypsin and papin. Leupeptin is well absorbed through oral route. Leupeptin has been known to cause various neuropathological changes in vivo rese...

mbling those of aging or neurodegenerative processes in the human brain, including the accumulation of neuronal processes and neuronal cytoskeletal abnormalities leading to neurofibrillary tangle (NFT)-like formations. In in vitro experiments, leupeptin protects the heart from myocardial stunning. Leupeptin was found to inhibit tumorigenesis in mouse skin induced by a single, noncarcinogenic dose of 7,12- dimethylbenz(a)anthracene followed by repeated application of croton oil. Tumors that had already been induced were scarcely affected by leupeptin.

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