U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Status:
US Previously Marketed
Source:
DYNACAINE W/EPINEPH PYRROCAINE by GRAHAM CHEM
(1962)
Source URL:
First approved in 1962
Source:
DYNACAINE W/EPINEPH PYRROCAINE by GRAHAM CHEM
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Pyrrocaine is the amide local anesthetics. It is metabolized to 2,6-xylidine. It was used mainly as an infiltration and nerve block dental anesthetic in the 1960s and favored due to its rapid onset. The potency of pyrrocaine equals that of lidocaine in both sensory and motor nerve blocking. Pyrrocaine provided to be somewhat less toxic than lidocaine. No methemoglobinemia was clinically observed. It has been classified as unsafe for use in acute porphyria. There is no evidence that it is currently used commercially.
Status:
US Previously Marketed
Source:
DYNACAINE W/EPINEPH PYRROCAINE by GRAHAM CHEM
(1962)
Source URL:
First approved in 1962
Source:
DYNACAINE W/EPINEPH PYRROCAINE by GRAHAM CHEM
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Pyrrocaine is the amide local anesthetics. It is metabolized to 2,6-xylidine. It was used mainly as an infiltration and nerve block dental anesthetic in the 1960s and favored due to its rapid onset. The potency of pyrrocaine equals that of lidocaine in both sensory and motor nerve blocking. Pyrrocaine provided to be somewhat less toxic than lidocaine. No methemoglobinemia was clinically observed. It has been classified as unsafe for use in acute porphyria. There is no evidence that it is currently used commercially.