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US Approved Rx

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Histamine H1 receptor

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EPINASTINE

Q13WX941EF

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Status:

US Approved Rx (2011)

First approved in 2003

Class (Stereo):

CHEMICAL (RACEMIC)

Targets:

Histamine H1 receptor

Conditions:

Allergic conjunctivitis

Epinastine (brand names Alesion, Elestat, Purivist, Relestat) is a second-generation antihistamine and mast cell stabilizer. Epinastine is a topically active, direct H1-receptor antagonist and an inhibitor of the release of histamine from the mast ce...

ll. Epinastine is selective for the histamine H1-receptor and has affinity for the histamine H2 receptor. Epinastine also possesses affinity for the α1-, α2-, and 5-HT2 –receptors. Epinastine does not penetrate the blood/brain barrier and, therefore, is not expected to induce side effects of the central nervous system. Elestat ophthalmic solution is indicated for the prevention of itching associated with allergic conjunctivitis.

EPINASTINE HYDROBROMIDE

4O6LIW7G3N

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Search for Structure

Status:

US Approved Rx (2011)

First approved in 2003

Class (Stereo):

CHEMICAL (RACEMIC)

Targets:

Histamine H1 receptor

Conditions:

Allergic conjunctivitis

Epinastine (brand names Alesion, Elestat, Purivist, Relestat) is a second-generation antihistamine and mast cell stabilizer. Epinastine is a topically active, direct H1-receptor antagonist and an inhibitor of the release of histamine from the mast ce...

ll. Epinastine is selective for the histamine H1-receptor and has affinity for the histamine H2 receptor. Epinastine also possesses affinity for the α1-, α2-, and 5-HT2 –receptors. Epinastine does not penetrate the blood/brain barrier and, therefore, is not expected to induce side effects of the central nervous system. Elestat ophthalmic solution is indicated for the prevention of itching associated with allergic conjunctivitis.

EPINASTINE HYDROCHLORIDE

GFM415S5XL

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Search for Structure

Status:

US Approved Rx (2011)

First approved in 2003

Class (Stereo):

CHEMICAL (RACEMIC)

Targets:

Histamine H1 receptor

Conditions:

Allergic conjunctivitis

Epinastine (brand names Alesion, Elestat, Purivist, Relestat) is a second-generation antihistamine and mast cell stabilizer. Epinastine is a topically active, direct H1-receptor antagonist and an inhibitor of the release of histamine from the mast ce...

ll. Epinastine is selective for the histamine H1-receptor and has affinity for the histamine H2 receptor. Epinastine also possesses affinity for the α1-, α2-, and 5-HT2 –receptors. Epinastine does not penetrate the blood/brain barrier and, therefore, is not expected to induce side effects of the central nervous system. Elestat ophthalmic solution is indicated for the prevention of itching associated with allergic conjunctivitis.

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