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Showing 1 - 2 of 2 results
Status:
Possibly Marketed Outside US
Source:
M020
(2024)
Source URL:
First approved in 2024
Source:
M020
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Dibenzoylmethane (DBM), a minor ingredient in licorice, is a calcium chelator that binds calcium through the β-diketone moiety, and it has been found to increase intracellular calcium concentrations in skeletal muscle cells. Intracellular calcium regulates the binding of Nrf2 to the HO-1 enhancer region. Both Nrf2 and HO-1 have been proposed as potential drug targets to prevent or treat liver disease. Thus was suggested DBM could be a lead/candidate for prevention or treatment of liver diseases. In addition, was found, that dibenzoylmethane inhibits mammary tumorigenesis, lymphomas, and leukemias in mice and it can prevent the formation of tumor-inducing DNA adducts.
Status:
Possibly Marketed Outside US
Source:
21 CFR 350
(2014)
Source URL:
First approved in 2014
Source:
21 CFR 350
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Zinc Palmitate is a cosmetic ingredient. Approved by FDA as indirect additive used in food contact substances. Zinc palmitate is also used as zinc precursor compound in preparation of Zinc oxide nanoparticles and nanostructures.