U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Nitrobenzene is an organic compound with an odor of bitter almonds, prepared by nitration of benzene. In chemical industry nitrobenzene is mainly used to produce aniline. It is also used in the synthesis of other organic compounds, including acetaminophen. Nitrobenzene is very toxic and can cause acute poisoning because it is readily absorbed via the skin or respiratory tract. The primary effects are lowering of the hemoglobin level, methemoglobinemia, cyanosis, and breathlessness. Chronic exposure can lead to spleen and liver damage, jaundice, and anemia. Ingestion of alcohol may speed up and exaggerate the effects.