U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
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Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)



Iniparib (BSI-201 or 4-iodo-3-nitrosobenzamide) inactivated poly(ADP-ribose) polymerase by zinc ejection from the first zinc finger of this nuclear protein. Iniparib, either alone or in combination with chemotherapy, had significant antitumor activi...