U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

A-784168 is a potent and selective antagonist of Vanilloid receptor type 1 (TRPV1). A-784168 has a good CNS penetration. Significant CNS penetration is necessary for a TRPV1 antagonist to produce broad-spectrum analgesia that was shown on animal models after oral administration of this compound.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)