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Status:
US Approved Rx (2017)
First approved in 2013

Class (Stereo):
CHEMICAL (ABSOLUTE)


Sofosbuvir is a nucleotide analog inhibitor of hepatitis C virus NS5B polymerase - the key enzyme mediating HCV RNA replication. Sofosbuvir is a prodrug and after ingestion it is rapidly converted to GS-331007, the predominant circulating drug that a...