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Development Status

Investigational

3

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Primary Target

Neuronal acetylcholine receptor protein alpha-7 subunit

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Highest Phase

Phase III

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Approval Year

Unknown

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Condition

Alzheimer’s disease

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Schizophrenia

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Treatment Modality

Primary

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CNS Activity

CNS Active

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Originator

Bayer

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Substance Class

Chemical

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Code System

CAS

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FDA UNII

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PUBCHEM

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SMS_ID

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ChEMBL

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Substance Form

Salts, Hydrates, Esters, etc.

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ENCENICLINE

5FI5376A0X

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Search for Structure

Status:

Investigational

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Neuronal acetylcholine receptor protein alpha-7 subunit

Conditions:

Alzheimer’s disease

Encenicline (EVP-6124; MT-4666) acts as a potent partial and selective agonist at alpha-7 nicotinic acetylcholine receptor. Encenicline significantly improved memory function in animal models. FORUM Pharmaceuticals (formerly EnVivo Pharmaceuticals) i...

s developing encenicline for the treatment of cognition disorders such as schizophrenia and for Alzheimer's disease.

ENCENICLINE HYDROCHLORIDE

VYV1YE9W06

Export Data
Search for Structure

Status:

Investigational

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Neuronal acetylcholine receptor protein alpha-7 subunit

Conditions:

Alzheimer’s disease

Encenicline (EVP-6124; MT-4666) acts as a potent partial and selective agonist at alpha-7 nicotinic acetylcholine receptor. Encenicline significantly improved memory function in animal models. FORUM Pharmaceuticals (formerly EnVivo Pharmaceuticals) i...

s developing encenicline for the treatment of cognition disorders such as schizophrenia and for Alzheimer's disease.

ENCENICLINE HYDROCHLORIDE MONOHYDRATE

9201D24ZB5

Export Data
Search for Structure

Status:

Investigational

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Neuronal acetylcholine receptor protein alpha-7 subunit

Conditions:

Alzheimer’s disease

Encenicline (EVP-6124; MT-4666) acts as a potent partial and selective agonist at alpha-7 nicotinic acetylcholine receptor. Encenicline significantly improved memory function in animal models. FORUM Pharmaceuticals (formerly EnVivo Pharmaceuticals) i...

s developing encenicline for the treatment of cognition disorders such as schizophrenia and for Alzheimer's disease.

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