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Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Tanespimycin (17-allylamino-17-demethoxygeldanamycin,
17-AAG) is a synthetic analogue of geldanamycin, an antibiotic
first purified in 1970 from Streptomyces hygroscopicus. Tanespimycin is an Hsp90 inhibitor that has demonstrated the potential to dis...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Soblidotin is a derivative of dolastatin 10, which was isolated from the Indian Ocean sea hare, Dolabella auricularia, in 1987. Soblidotin inhibits tubulin polymerization, resulting in cell cycle arrest and induction of apoptosis. It has a broad spec...