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US Previously Marketed

8

Other

2

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Primary Target

Bacterial dihydropteroate synthase

7

Escherichia coli

7

folic acid biosynthetic process

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Highest Phase

Approved

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Approval Year

1940

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Unknown

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1921

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Condition

Vaginal infections

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Treatment Modality

Curative

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Originator

Fosbinder, R.J.|Walter, L.A.

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Chemical

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CAS

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FDA UNII

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EPA CompTox

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ECHA (EC/EINECS)

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ATC Level 1

ALIMENTARY TRACT AND METABOLISM

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ANTIINFECTIVES FOR SYSTEMIC USE

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DERMATOLOGICALS

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ATC Level 2

ANTIBACTERIALS FOR SYSTEMIC USE

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ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE

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ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS

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ATC Level 3

CHEMOTHERAPEUTICS FOR TOPICAL USE

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INTESTINAL ANTIINFECTIVES

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SULFONAMIDES AND TRIMETHOPRIM

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ATC Level 4

Sulfonamides

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Short-acting sulfonamides

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Substance Form

Salts, Hydrates, Esters, etc.

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Showing 1 - 10 of 10 results

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3-PYRROLIDINECARBOXYLIC ACID

XQ9918NB1D

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Status:

Other

Class (Stereo):

CHEMICAL (RACEMIC)

METHYL 3-BROMOPROPANOATE

Y803CH1P4W

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

SULFATHIAZOLE

Y7FKS2XWQH

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Status:

US Previously Marketed

First approved in 1940

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Escherichia coli

folic acid biosynthetic process

Bacterial dihydropteroate synthase

Escherichia coli

Conditions:

Vaginal infections

Sulfathiazole is a short-acting sulfonamide with properties similar to those of sulfamethoxazole. It is now rarely used systemically due to its toxicity. Sulfathiazole is used with other sulfonamides, usually sulfabenzamide and sulfacetamide, in prep...

arations for the topical treatment of vaginal infections and is also used with other drugs in the treatment of skin infections. Sulfathiazole sodium has been applied topically with other drugs in the treatment of eye infections. Sulfathiazole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid.It has properties similar to sulfamethoxazole.

PHOSPHORUS

27YLU75U4W

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Status:

US Previously Marketed

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Phosphorus is a chemical element with symbol P and atomic number 15. Phosphorus is essential for life (compounds containing the phosphate ion) are a component of DNA, RNA, ATP, and phospholipids. Elemental phosphorus exists in many allotropic forms, ...

three major allotropes are white, red and black. Red phosphorus is a component of matchbook strike plates and is used as an ingredient in certain commercial rat and cockroach poisons. Red phosphorus is used in the manufacture of pyrotechnics, safety matches, semiconductors, fertilizers, pesticides, incendiary shells, smoke bombs, and tracer bullets. It is also used in organic synthesis reactions and in the manufacture of phosphoric acid, phosphine, phosphoric anhydride, phosphorus pentachloride, and phosphorus trichloride. Red phosphorus is also used in electroluminescent coatings and in flame retardants for polymers.

SUCCINYLSULFATHIAZOLE

RSS8647O4S

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Status:

US Previously Marketed

First approved in 1940

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Escherichia coli

folic acid biosynthetic process

Bacterial dihydropteroate synthase

Escherichia coli

Conditions:

Vaginal infections

Sulfathiazole is a short-acting sulfonamide with properties similar to those of sulfamethoxazole. It is now rarely used systemically due to its toxicity. Sulfathiazole is used with other sulfonamides, usually sulfabenzamide and sulfacetamide, in prep...

arations for the topical treatment of vaginal infections and is also used with other drugs in the treatment of skin infections. Sulfathiazole sodium has been applied topically with other drugs in the treatment of eye infections. Sulfathiazole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid.It has properties similar to sulfamethoxazole.

SULPHATHIAZOLE SODIUM PENTAHYDRATE

ST7PF0D71H

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Status:

US Previously Marketed

First approved in 1940

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Escherichia coli

folic acid biosynthetic process

Bacterial dihydropteroate synthase

Escherichia coli

Conditions:

Vaginal infections

Sulfathiazole is a short-acting sulfonamide with properties similar to those of sulfamethoxazole. It is now rarely used systemically due to its toxicity. Sulfathiazole is used with other sulfonamides, usually sulfabenzamide and sulfacetamide, in prep...

arations for the topical treatment of vaginal infections and is also used with other drugs in the treatment of skin infections. Sulfathiazole sodium has been applied topically with other drugs in the treatment of eye infections. Sulfathiazole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid.It has properties similar to sulfamethoxazole.

SUCCINYLSULFATHIAZOLE MONOHYDRATE

HM7K18OJZ9

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Status:

US Previously Marketed

First approved in 1940

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Escherichia coli

folic acid biosynthetic process

Bacterial dihydropteroate synthase

Escherichia coli

Conditions:

Vaginal infections

Sulfathiazole is a short-acting sulfonamide with properties similar to those of sulfamethoxazole. It is now rarely used systemically due to its toxicity. Sulfathiazole is used with other sulfonamides, usually sulfabenzamide and sulfacetamide, in prep...

arations for the topical treatment of vaginal infections and is also used with other drugs in the treatment of skin infections. Sulfathiazole sodium has been applied topically with other drugs in the treatment of eye infections. Sulfathiazole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid.It has properties similar to sulfamethoxazole.

SULFATHIAZOLE SODIUM MONOHYDRATE

W6NDW4K12P

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Status:

US Previously Marketed

First approved in 1940

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Escherichia coli

folic acid biosynthetic process

Bacterial dihydropteroate synthase

Escherichia coli

Conditions:

Vaginal infections

Sulfathiazole is a short-acting sulfonamide with properties similar to those of sulfamethoxazole. It is now rarely used systemically due to its toxicity. Sulfathiazole is used with other sulfonamides, usually sulfabenzamide and sulfacetamide, in prep...

arations for the topical treatment of vaginal infections and is also used with other drugs in the treatment of skin infections. Sulfathiazole sodium has been applied topically with other drugs in the treatment of eye infections. Sulfathiazole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid.It has properties similar to sulfamethoxazole.

SULFATHIAZOLE ZINC

4KCI0QUF9Q

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Status:

US Previously Marketed

First approved in 1940

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Escherichia coli

folic acid biosynthetic process

Bacterial dihydropteroate synthase

Escherichia coli

Conditions:

Vaginal infections

Sulfathiazole is a short-acting sulfonamide with properties similar to those of sulfamethoxazole. It is now rarely used systemically due to its toxicity. Sulfathiazole is used with other sulfonamides, usually sulfabenzamide and sulfacetamide, in prep...

arations for the topical treatment of vaginal infections and is also used with other drugs in the treatment of skin infections. Sulfathiazole sodium has been applied topically with other drugs in the treatment of eye infections. Sulfathiazole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid.It has properties similar to sulfamethoxazole.

SULFATHIAZOLE SODIUM

PV16N742VM

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Status:

US Previously Marketed

First approved in 1940

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Escherichia coli

folic acid biosynthetic process

Bacterial dihydropteroate synthase

Escherichia coli

Conditions:

Vaginal infections

Sulfathiazole is a short-acting sulfonamide with properties similar to those of sulfamethoxazole. It is now rarely used systemically due to its toxicity. Sulfathiazole is used with other sulfonamides, usually sulfabenzamide and sulfacetamide, in prep...

arations for the topical treatment of vaginal infections and is also used with other drugs in the treatment of skin infections. Sulfathiazole sodium has been applied topically with other drugs in the treatment of eye infections. Sulfathiazole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid.It has properties similar to sulfamethoxazole.

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