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Development Status

Other

2

Designated

1

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Primary Target

Elongation step of polypeptide synthesis

1

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Approval Year

Unknown

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Condition

Proximal spinal muscular atrophy

1

Salmonellosis

1

Vaginal trichomoniasis

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Treatment Modality

Curative

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Primary

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Originator

Wagman, G.H. et al.

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Substance Class

Chemical

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Code System

CAS

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EPA CompTox

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FDA UNII

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PUBCHEM

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CHEBI

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Principal Form

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Showing 1 - 3 of 3 results

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GENETICIN

A08F5XTI6G

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Status:

Designated

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Elongation step of polypeptide synthesis

Conditions:

Vaginal trichomoniasis

Proximal spinal muscular atrophy

Geneticin (G-418) is produced by Micromonospora phodorangea. The antibiotic has brad spectrum antibacterial activity similar to gentamicins and other previously described aminoglycosides but of particular interest because of its high activity against...

protozoa, amoebae, tapeworm and pinworm infections in mice. G418 blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. G418 is commonly used in laboratory research to select genetically engineered cells.

PYRIDINIUM DICHROMATE

Y7AV7UFN7K

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

1,1,1-TRIMETHOXYETHANE

04H7A3FK37

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

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