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Showing 1 - 4 of 4 results
Status:
Investigational
Source:
NCT04106557: Phase 3 Interventional Completed Primary Disease or Condition Being Studied: Angelman Syndrome (AS)
(2019)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Gaboxadol (or THIP) is a direct GABA mimetic ligand at delta-containing receptors. Gaboxadol went into human clinical trials to test if the drug promoted sleep. It was generally well tolerated. Gaboxadol enhances delta power in NREM sleep in humans. Gaboxadol failed in Phase III for sleep studies. The side effects of Gaboxadol have been described as mild and similar in quality to those of other GABA-mimetics. Gaboxadol is in development with Ovid Therapeutics as a treatment for Angelman syndrome, fragile X syndrome and epilepsy.
Status:
Investigational
Source:
NCT04106557: Phase 3 Interventional Completed Primary Disease or Condition Being Studied: Angelman Syndrome (AS)
(2019)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Gaboxadol (or THIP) is a direct GABA mimetic ligand at delta-containing receptors. Gaboxadol went into human clinical trials to test if the drug promoted sleep. It was generally well tolerated. Gaboxadol enhances delta power in NREM sleep in humans. Gaboxadol failed in Phase III for sleep studies. The side effects of Gaboxadol have been described as mild and similar in quality to those of other GABA-mimetics. Gaboxadol is in development with Ovid Therapeutics as a treatment for Angelman syndrome, fragile X syndrome and epilepsy.
Status:
Investigational
Source:
NCT04106557: Phase 3 Interventional Completed Primary Disease or Condition Being Studied: Angelman Syndrome (AS)
(2019)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Gaboxadol (or THIP) is a direct GABA mimetic ligand at delta-containing receptors. Gaboxadol went into human clinical trials to test if the drug promoted sleep. It was generally well tolerated. Gaboxadol enhances delta power in NREM sleep in humans. Gaboxadol failed in Phase III for sleep studies. The side effects of Gaboxadol have been described as mild and similar in quality to those of other GABA-mimetics. Gaboxadol is in development with Ovid Therapeutics as a treatment for Angelman syndrome, fragile X syndrome and epilepsy.
Status:
Investigational
Source:
NCT04106557: Phase 3 Interventional Completed Primary Disease or Condition Being Studied: Angelman Syndrome (AS)
(2019)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Gaboxadol (or THIP) is a direct GABA mimetic ligand at delta-containing receptors. Gaboxadol went into human clinical trials to test if the drug promoted sleep. It was generally well tolerated. Gaboxadol enhances delta power in NREM sleep in humans. Gaboxadol failed in Phase III for sleep studies. The side effects of Gaboxadol have been described as mild and similar in quality to those of other GABA-mimetics. Gaboxadol is in development with Ovid Therapeutics as a treatment for Angelman syndrome, fragile X syndrome and epilepsy.
