Inxight Drugs

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Return Home Inxight Drugs

Home
Browse Drugs
Search
- Structure Search
- Sequence Search
Downloads
About

Show Filters

Hide Filters

Development Status

Investigational

1

Other

1

All Match

Any Match

Exclude Selected

Exclude Selected

Primary Target

Sodium channel protein type II alpha subunit

1

Sodium channel protein type III alpha subunit

1

Voltage-gated L-type calcium channel

1

Voltage-gated N-type calcium channel alpha-1B subunit

1

Voltage-gated P/Q-type calcium channel alpha-1A subunit

1

All Match

Any Match

Exclude Selected

Exclude Selected

Approval Year

Unknown

2

All Match

Any Match

Exclude Selected

Exclude Selected

CNS Activity

CNS Active

1

All Match

Any Match

Exclude Selected

Exclude Selected

Originator

Jazz Pharmaceuticals

1

All Match

Any Match

Exclude Selected

Exclude Selected

Substance Class

Chemical

2

All Match

Any Match

Exclude Selected

Exclude Selected

Code System

CAS

2

FDA UNII

2

PUBCHEM

2

ChEMBL

1

EPA CompTox

1

All Match

Any Match

Exclude Selected

Exclude Selected

Substance Form

Principal Form

2

All Match

Any Match

Exclude Selected

Exclude Selected

Showing 1 - 2 of 2 results

First page disabled
Previous page disabled
1
Next page disabled
Next page disabled

ELPETRIGINE

1X64S9H3ZS

Export Data
Search for Structure

Status:

Investigational

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Sodium channel protein type II alpha subunit

Sodium channel protein type III alpha subunit

Voltage-gated L-type calcium channel

Voltage-gated N-type calcium channel alpha-1B subunit

Voltage-gated P/Q-type calcium channel alpha-1A subunit

Elpetrigine (GW293273 or JZP-4) is potent calcium and sodium channel blocker. In animal models, elpetrigine exerts anxiolytic, anticonvulsant, antidepressant and antimania effects. Jazz Pharmaceuticals is developing elpetrigine for the treatment of m...

ood disorders and epilepsy.

5-METHYLISOXAZOLE-4-CARBOXYLIC ACID

BL2Q213Q2M

Export Data
Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

HHS VULNERABILITY DISCLOSURE

For language access assistance, contact the NCATS Public Information Officer

National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966


			version 1.1