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Showing 1 - 5 of 5 results
4-Amino-2-nitrophenol is a brownish yellow compound used as an industrial dye intermediate and as a constituent of "semi-permanent" hair dyes under a trade name Rodol 42. 4-Amino-2-nitrophenol is formulated without an oxidizing agent. It is used in concentrations estimated at 0.1-1.0% in the "semi-permanent" hair dyes, which are applied as shampoos and remain on the hair for 20-40 minutes before they are rinsed out. Several toxicological studies suggested potential carcinogenicity and mutagenicity concerns for 4-Amino-2-nitrophenol.
Status:
Possibly Marketed Outside US
Source:
NCT03238105: Phase 4 Interventional Unknown status Periorbital Disorder
(2017)
Source URL:
First approved in 2020
Source:
21 CFR 333A
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Thioglycolic acid (TGA, also known as MERCAPTOACETIC ACID) is widely used in the hairdressing industry, which mostly caters to women. TGA has been reported to impair several organs, especially reproductive ones such as testes and ovaries. Thioglycolates (the salt forms of TGA) was shown to penetrate the skin and distribute to the kidneys, lungs, small intestine, and spleen; excretion is primarily in the urine. In addition, thioglycolates can be skin irritants of an animal and can be sensitizers.
Status:
Possibly Marketed Outside US
Source:
NCT03238105: Phase 4 Interventional Unknown status Periorbital Disorder
(2017)
Source URL:
First approved in 2020
Source:
21 CFR 333A
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Thioglycolic acid (TGA, also known as MERCAPTOACETIC ACID) is widely used in the hairdressing industry, which mostly caters to women. TGA has been reported to impair several organs, especially reproductive ones such as testes and ovaries. Thioglycolates (the salt forms of TGA) was shown to penetrate the skin and distribute to the kidneys, lungs, small intestine, and spleen; excretion is primarily in the urine. In addition, thioglycolates can be skin irritants of an animal and can be sensitizers.
Status:
Possibly Marketed Outside US
Source:
NCT03238105: Phase 4 Interventional Unknown status Periorbital Disorder
(2017)
Source URL:
First approved in 2020
Source:
21 CFR 333A
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Thioglycolic acid (TGA, also known as MERCAPTOACETIC ACID) is widely used in the hairdressing industry, which mostly caters to women. TGA has been reported to impair several organs, especially reproductive ones such as testes and ovaries. Thioglycolates (the salt forms of TGA) was shown to penetrate the skin and distribute to the kidneys, lungs, small intestine, and spleen; excretion is primarily in the urine. In addition, thioglycolates can be skin irritants of an animal and can be sensitizers.
Status:
Possibly Marketed Outside US
Source:
NCT03238105: Phase 4 Interventional Unknown status Periorbital Disorder
(2017)
Source URL:
First approved in 2020
Source:
21 CFR 333A
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Thioglycolic acid (TGA, also known as MERCAPTOACETIC ACID) is widely used in the hairdressing industry, which mostly caters to women. TGA has been reported to impair several organs, especially reproductive ones such as testes and ovaries. Thioglycolates (the salt forms of TGA) was shown to penetrate the skin and distribute to the kidneys, lungs, small intestine, and spleen; excretion is primarily in the urine. In addition, thioglycolates can be skin irritants of an animal and can be sensitizers.
