JNJ-5207852 is a novel, non-imidazole histamine H3 receptor antagonist, with high affinity at human (pKi=9.24) H3 receptor and was developed by Johnson & Johnson Pharmaceutical. During preclinical studies were shown that JNJ-5207852 might be useful in the treatment of cognitive impairment in epilepsy. On animal models was discovered, that this compound readily penetrates the brain tissue after subcutaneous administration.

Anabasine, a tobacco alkaloid, was used as a biomarker of active tobacco use. Anabasine is a selective alpha7-nicotinic acetylcholine receptor agonist. Anabasine antagonized MK-801-elicited mouse popping behavior, an animal model of schizophrenia.

Phosphorus is a chemical element with symbol P and atomic number 15. Phosphorus is essential for life (compounds containing the phosphate ion) are a component of DNA, RNA, ATP, and phospholipids. Elemental phosphorus exists in many allotropic forms, three major allotropes are white, red and black. Red phosphorus is a component of matchbook strike plates and is used as an ingredient in certain commercial rat and cockroach poisons. Red phosphorus is used in the manufacture of pyrotechnics, safety matches, semiconductors, fertilizers, pesticides, incendiary shells, smoke bombs, and tracer bullets. It is also used in organic synthesis reactions and in the manufacture of phosphoric acid, phosphine, phosphoric anhydride, phosphorus pentachloride, and phosphorus trichloride. Red phosphorus is also used in electroluminescent coatings and in flame retardants for polymers.

Anabasine, a tobacco alkaloid, was used as a biomarker of active tobacco use. Anabasine is a selective alpha7-nicotinic acetylcholine receptor agonist. Anabasine antagonized MK-801-elicited mouse popping behavior, an animal model of schizophrenia.

Anabasine, a tobacco alkaloid, was used as a biomarker of active tobacco use. Anabasine is a selective alpha7-nicotinic acetylcholine receptor agonist. Anabasine antagonized MK-801-elicited mouse popping behavior, an animal model of schizophrenia.