U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Status:
Investigational
Source:
INN:declenperone
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Declenperone is an antagonist of 5-HT2 receptors, developed by Janssen Pharmaceutica. The compound is claimed to have strong neuroleptic activity, as evidenced by experimental data obtained in apomorphine-tryptamine and norepinephrine test in rats, and the apomorphine test in dogs. Declenperone was used in a veterinary as a sedative.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Ethylene oxide (oxirane) is the simplest cyclic ether. It is a colorless gas or liquid and has a sweet, etheric odor. Ethylene oxide is an important raw material used in the manufacture of chemical derivatives. Ethylene oxide is very reactive because its highly strained ring can be opened easily, and is thus one of the most versatile chemical intermediates. The ability of ethylene oxide to damage DNA makes it an effective sterilizing agent but also accounts for its cancer-causing activity.