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Development Status

US Approved OTC

18

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Primary Target

Prostaglandin G/H synthase 1

18

Prostaglandin G/H synthase 2

18

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Highest Phase

Approved

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Approval Year

1899

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Condition

Headache

18

Myocardial infarction

18

Pain

18

Stroke

18

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Treatment Modality

Preventing

18

Primary

18

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CNS Activity

CNS Penetrant

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Originator

Bayer

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Substance Class

Chemical

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INN Stem

Chemical substance(-ine)

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Code System

CAS

18

FDA UNII

18

PUBCHEM

18

EPA CompTox

17

SMS_ID

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ATC Level 1

BLOOD AND BLOOD FORMING ORGANS

3

NERVOUS SYSTEM

3

ALIMENTARY TRACT AND METABOLISM

1

CARDIOVASCULAR SYSTEM

1

MUSCULO-SKELETAL SYSTEM

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ATC Level 2

ANALGESICS

3

ANTITHROMBOTIC AGENTS

3

ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS

1

BETA BLOCKING AGENTS

1

LIPID MODIFYING AGENTS

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ATC Level 3

ANTITHROMBOTIC AGENTS

3

OTHER ANALGESICS AND ANTIPYRETICS

3

ANTIINFLAMMATORY/ANTIRHEUMATIC AGENTS IN COMBINATION

1

BETA BLOCKING AGENTS, OTHER COMBINATIONS

1

LIPID MODIFYING AGENTS, COMBINATIONS

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ATC Level 4

Platelet aggregation inhibitors excl. heparin

3

Salicylic acid and derivatives

3

Antiinflammatory/antirheumatic agents in combination with corticosteroids

1

Beta blocking agents, other combinations

1

HMG CoA reductase inhibitors, other combinations

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Substance Form

Salts, Hydrates, Esters, etc.

17

Principal Form

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Showing 1 - 10 of 18 results

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ASPIRIN ALUMINUM

E33TS05V6B

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Status:

US Approved OTC

First marketed in 1899

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Prostaglandin G/H synthase 2

Prostaglandin G/H synthase 1

Conditions:

Myocardial infarction

Aspirin is a nonsteroidal anti-inflammatory drug. Aspirin is unique in this class of drugs because it irreversibly inhibits both COX-1 and COX-2 activity by acetylating a serine residue (Ser529 and Ser516, respectively) positioned in the arachidonic ...

acid-binding channel, thus inhibiting the synthesis of prostaglandins and reducing the inflammatory response. The drug is used either alone or in combination with other compounds for the treatment of pain, headache, as well as for reducing the risk of stroke and heart attacks in patients with brain ischemia and cardiovascular diseases.

DIHYDROXYALUMINUM ASPIRIN

20D04M9OLN

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Status:

US Approved OTC

First marketed in 1899

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Prostaglandin G/H synthase 2

Prostaglandin G/H synthase 1

Conditions:

Myocardial infarction

Aspirin is a nonsteroidal anti-inflammatory drug. Aspirin is unique in this class of drugs because it irreversibly inhibits both COX-1 and COX-2 activity by acetylating a serine residue (Ser529 and Ser516, respectively) positioned in the arachidonic ...

acid-binding channel, thus inhibiting the synthesis of prostaglandins and reducing the inflammatory response. The drug is used either alone or in combination with other compounds for the treatment of pain, headache, as well as for reducing the risk of stroke and heart attacks in patients with brain ischemia and cardiovascular diseases.

ALUMINUM ACETYLSALICYLATE

ED7L5F608H

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Status:

US Approved OTC

First marketed in 1899

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Prostaglandin G/H synthase 2

Prostaglandin G/H synthase 1

Conditions:

Myocardial infarction

Aspirin is a nonsteroidal anti-inflammatory drug. Aspirin is unique in this class of drugs because it irreversibly inhibits both COX-1 and COX-2 activity by acetylating a serine residue (Ser529 and Ser516, respectively) positioned in the arachidonic ...

acid-binding channel, thus inhibiting the synthesis of prostaglandins and reducing the inflammatory response. The drug is used either alone or in combination with other compounds for the treatment of pain, headache, as well as for reducing the risk of stroke and heart attacks in patients with brain ischemia and cardiovascular diseases.

Aspirin Trelamine Hydrochloride

J0TQX5LV1L

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Status:

US Approved OTC

First marketed in 1899

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Prostaglandin G/H synthase 2

Prostaglandin G/H synthase 1

Conditions:

Myocardial infarction

Aspirin is a nonsteroidal anti-inflammatory drug. Aspirin is unique in this class of drugs because it irreversibly inhibits both COX-1 and COX-2 activity by acetylating a serine residue (Ser529 and Ser516, respectively) positioned in the arachidonic ...

acid-binding channel, thus inhibiting the synthesis of prostaglandins and reducing the inflammatory response. The drug is used either alone or in combination with other compounds for the treatment of pain, headache, as well as for reducing the risk of stroke and heart attacks in patients with brain ischemia and cardiovascular diseases.

ASPIRIN ARGININE

4FES8WRA60

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Status:

US Approved OTC

First marketed in 1899

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Prostaglandin G/H synthase 2

Prostaglandin G/H synthase 1

Conditions:

Myocardial infarction

Aspirin is a nonsteroidal anti-inflammatory drug. Aspirin is unique in this class of drugs because it irreversibly inhibits both COX-1 and COX-2 activity by acetylating a serine residue (Ser529 and Ser516, respectively) positioned in the arachidonic ...

acid-binding channel, thus inhibiting the synthesis of prostaglandins and reducing the inflammatory response. The drug is used either alone or in combination with other compounds for the treatment of pain, headache, as well as for reducing the risk of stroke and heart attacks in patients with brain ischemia and cardiovascular diseases.

CARBASPIRIN

73J0P7720Y

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Status:

US Approved OTC

First marketed in 1899

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Prostaglandin G/H synthase 2

Prostaglandin G/H synthase 1

Conditions:

Myocardial infarction

Aspirin is a nonsteroidal anti-inflammatory drug. Aspirin is unique in this class of drugs because it irreversibly inhibits both COX-1 and COX-2 activity by acetylating a serine residue (Ser529 and Ser516, respectively) positioned in the arachidonic ...

acid-binding channel, thus inhibiting the synthesis of prostaglandins and reducing the inflammatory response. The drug is used either alone or in combination with other compounds for the treatment of pain, headache, as well as for reducing the risk of stroke and heart attacks in patients with brain ischemia and cardiovascular diseases.

ALOXIPRIN

6QT214X4XU

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Status:

US Approved OTC

First marketed in 1899

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Prostaglandin G/H synthase 2

Prostaglandin G/H synthase 1

Conditions:

Myocardial infarction

Aspirin is a nonsteroidal anti-inflammatory drug. Aspirin is unique in this class of drugs because it irreversibly inhibits both COX-1 and COX-2 activity by acetylating a serine residue (Ser529 and Ser516, respectively) positioned in the arachidonic ...

acid-binding channel, thus inhibiting the synthesis of prostaglandins and reducing the inflammatory response. The drug is used either alone or in combination with other compounds for the treatment of pain, headache, as well as for reducing the risk of stroke and heart attacks in patients with brain ischemia and cardiovascular diseases.

ASPIRIN DL-LYSINE

2JJ274J145

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Status:

US Approved OTC

First marketed in 1899

Class (Stereo):

CHEMICAL (RACEMIC)

Targets:

Prostaglandin G/H synthase 2

Prostaglandin G/H synthase 1

Conditions:

Myocardial infarction

Aspirin is a nonsteroidal anti-inflammatory drug. Aspirin is unique in this class of drugs because it irreversibly inhibits both COX-1 and COX-2 activity by acetylating a serine residue (Ser529 and Ser516, respectively) positioned in the arachidonic ...

acid-binding channel, thus inhibiting the synthesis of prostaglandins and reducing the inflammatory response. The drug is used either alone or in combination with other compounds for the treatment of pain, headache, as well as for reducing the risk of stroke and heart attacks in patients with brain ischemia and cardiovascular diseases.

ASPIRIN COPPER

5DR11472UI

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Status:

US Approved OTC

First marketed in 1899

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Prostaglandin G/H synthase 2

Prostaglandin G/H synthase 1

Conditions:

Myocardial infarction

Aspirin is a nonsteroidal anti-inflammatory drug. Aspirin is unique in this class of drugs because it irreversibly inhibits both COX-1 and COX-2 activity by acetylating a serine residue (Ser529 and Ser516, respectively) positioned in the arachidonic ...

acid-binding channel, thus inhibiting the synthesis of prostaglandins and reducing the inflammatory response. The drug is used either alone or in combination with other compounds for the treatment of pain, headache, as well as for reducing the risk of stroke and heart attacks in patients with brain ischemia and cardiovascular diseases.

Aspirin Trelamine

JKW59XM343

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Status:

US Approved OTC

First marketed in 1899

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Prostaglandin G/H synthase 2

Prostaglandin G/H synthase 1

Conditions:

Myocardial infarction

Aspirin is a nonsteroidal anti-inflammatory drug. Aspirin is unique in this class of drugs because it irreversibly inhibits both COX-1 and COX-2 activity by acetylating a serine residue (Ser529 and Ser516, respectively) positioned in the arachidonic ...

acid-binding channel, thus inhibiting the synthesis of prostaglandins and reducing the inflammatory response. The drug is used either alone or in combination with other compounds for the treatment of pain, headache, as well as for reducing the risk of stroke and heart attacks in patients with brain ischemia and cardiovascular diseases.

Showing 1 - 10 of 18 results

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