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Originator

Institut Gustave-Roussy|Sanofi

2

Pfizer

420

Eli Lilly

239

Merck

238

GlaxoSmithKline

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Possibly Marketed Outside US

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DNA

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DNA topoisomerase II

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Approved

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Unknown

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Condition

Breast cancer

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Primary

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Chemical

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CAS

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EVMPD

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MESH

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NCI_THESAURUS

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Salts, Hydrates, Esters, etc.

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ELLIPTINIUM

1F1959S062

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Status:

Possibly Marketed Outside US

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

DNA topoisomerase II

Conditions:

Elliptinium is an antineoplastic agent, which was used in the treatment of metastatic breast cancer in France under the name Celiptium. The drug is known to intercalate into DNA and inhibit topoisomerase II. Several studies have demonstrated that thi...

s molecule can be oxidized, yielding a reactive electrophilic form, which is able to bind covalently to a nucleophilic biological molecule.

ELLIPTINIUM ACETATE

H9B41234P4

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Status:

Possibly Marketed Outside US

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

DNA topoisomerase II

Conditions:

Elliptinium is an antineoplastic agent, which was used in the treatment of metastatic breast cancer in France under the name Celiptium. The drug is known to intercalate into DNA and inhibit topoisomerase II. Several studies have demonstrated that thi...

s molecule can be oxidized, yielding a reactive electrophilic form, which is able to bind covalently to a nucleophilic biological molecule.

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