U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
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Showing 1 - 10 of 19 results

Status:
US Approved Rx (2000)
First approved in 1994

Class (Stereo):
CHEMICAL (RACEMIC)



Salmeterol is a long-acting beta2-adrenergic agonist. Although beta2-adrenoceptors are the predominant adrenergic receptors in bronchial smooth muscle and beta1-adrenoceptors are the predominant receptors in the heart, there are also beta2-adrenocept...
Status:
US Approved Rx (2021)
First approved in 1992

Class (Stereo):
CHEMICAL (ACHIRAL)



Sumatriptan is a serotonin (5-HT1B/1D) receptor agonist indicated for acute treatment of migraine with or without aura in adults. Sumatriptan is structurally similar to serotonin (5-HT), and is a 5-HT receptor (types 5-HT1D and 5-HT1B) agonist. The ...
Status:
US Approved Rx (2015)
First approved in 1985

Class (Stereo):
CHEMICAL (ABSOLUTE)



Ceftazidime is a semisynthetic, broad-spectrum, beta-lactam antibiotic, used especially for Pseudomonas and other gram-negative infections in debilitated patients. Ceftazidime is used to treat lower respiratory tract, skin, urinary tract, blood-strea...
Status:
US Approved Rx (2003)
First approved in 1983

Class (Stereo):
CHEMICAL (ABSOLUTE)



Cefuroxime is a semisynthetic, broad-spectrum, cephalosporin antibiotic. Cefuroxime is a bactericidal agent that acts by inhibition of bacterial cell wall synthesis. Cefuroxime has activity in the presence of some beta-lactamases, both penicillinases...
GR 103691 is an effective and selective receptor antagonist of the D3DR (dopamine D3 receptor). GR 103691 was shown to have 100-fold higher selectivity for D3DR (dopamine D3 receptor) over the D2DR (dopamine D2 receptor) and D4DR (dopamine D4 recepto...
GW627368 is a novel, potent and selective competitive antagonist of prostanoid EP4 receptor with additional human prostanoid TP receptor affinity. GW627368X effectively inhibits tumor survival, motility, proliferation and angiogenesis by blocking EP4...
Status:
US Previously Marketed
First approved in 1968

Class (Stereo):
CHEMICAL (ABSOLUTE)



Cephaloridine (or cefaloridine) is a first generation semisynthetic derivative of cephalosporin C. It is unique among cephalosporins in that it exists as a zwitterion. It is of semi synthetic origin and belongs to cephem carboxylate. It belongs to Pe...
Status:
Possibly Marketed Outside US
First approved in 2018

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Alfaxalone is a rapidly acting hydrophobic synthetic neurosteroid. It is indicated for the induction and maintenance of anesthesia and for induction of anesthesia followed by maintenance with an inhalant anesthetic, in cats and dogs. Alfaxalone induc...
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ABSOLUTE)



Nitrocefin is a chromogenic cephalosporin substrate routinely used to detect the presence of beta-lactamase enzymes produced by various microbes. Intact beta-lactam antibiotics act as an analog to penicillin-binding proteins (PBPs) involved in peptid...
Status:
US Approved Rx (2000)
First approved in 1994

Class (Stereo):
CHEMICAL (RACEMIC)



Salmeterol is a long-acting beta2-adrenergic agonist. Although beta2-adrenoceptors are the predominant adrenergic receptors in bronchial smooth muscle and beta1-adrenoceptors are the predominant receptors in the heart, there are also beta2-adrenocept...

Showing 1 - 10 of 19 results