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Originator

Enss, H. et al.

2

Pfizer

420

Eli Lilly

239

Merck

238

GlaxoSmithKline

197

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Possibly Marketed Outside US

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Primary Target

Cytochrome P450 1A2

2

Cytochrome P450 2B, Rattus norvegicus

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Dopamine D2 receptor

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Unknown

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Schizophrenia

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Primary

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CNS Active

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ATC Level 4

Phenothiazines with piperazine structure

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Salts, Hydrates, Esters, etc.

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PERAZINE

8915147A2B

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Status:

Possibly Marketed Outside US

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Cytochrome P450 1A2

Dopamine D2 receptor

Cytochrome P450 2B, Rattus norvegicus

Conditions:

Perazine (Taxilan) is a moderate-potency typical antipsychotic of the phenothiazine class. Perazine is an older antipsychotic drug first introduced in the 1950s. It is suggested to have a low level of side effects (especially for movement disorders)....

Its use is regional and restricted to countries like Germany, Poland, the Netherlands and the former Yugoslavia. Perazine has being shown to be a potent inhibitor of human CYP1A2. It acts as a dopamine antagonist.

PERAZINE DIMALEATE

3VG1507988

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Status:

Possibly Marketed Outside US

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Cytochrome P450 1A2

Dopamine D2 receptor

Cytochrome P450 2B, Rattus norvegicus

Conditions:

Perazine (Taxilan) is a moderate-potency typical antipsychotic of the phenothiazine class. Perazine is an older antipsychotic drug first introduced in the 1950s. It is suggested to have a low level of side effects (especially for movement disorders)....

Its use is regional and restricted to countries like Germany, Poland, the Netherlands and the former Yugoslavia. Perazine has being shown to be a potent inhibitor of human CYP1A2. It acts as a dopamine antagonist.

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