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Showing 1 - 4 of 4 results

Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)



CHF-5074 is a small molecule with a unique microglial modulating mechanism of action capable of selectively reducing pro-inflammatory activities of microglial cells while increasing their ability to remove neurotoxic amyloid beta (“Aβ”) aggregates in...
Status:
Investigational

Class (Stereo):
CHEMICAL (RACEMIC)

Nolomirole (CHF1035) is an orally active, selective dopamine agonist, primarily activating DA2- and alpha2 receptors, thereby inhibiting norepinephrine release, which may be beneficial in heart failure. Nolomirole is able to attenuate the heart failu...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)

Terestigmine (also known as CHF-2060), a cholinesterase inhibitor, was developed for the treatment of cognition disorders in Italy. However, this study was discontinued.
Status:
Investigational

Class (Stereo):
CHEMICAL (RACEMIC)

Nolomirole (CHF1035) is an orally active, selective dopamine agonist, primarily activating DA2- and alpha2 receptors, thereby inhibiting norepinephrine release, which may be beneficial in heart failure. Nolomirole is able to attenuate the heart failu...