U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 251 - 260 of 12951 results

Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

LAURALKONIUM is an antiseptic.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Possibly Marketed Outside US
Source:
Sodium Sulfacetamide and Sulfur by Bryant Ranch Prepack
(2021)
Source URL:
First approved in 2021
Source:
Sodium Sulfacetamide and Sulfur by Bryant Ranch Prepack
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Status:
Possibly Marketed Outside US
Source:
LAGEVRIO by Merck Sharp & Dohme LLC
(2021)
Source URL:
First approved in 2021

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Possibly Marketed Outside US
Source:
Hepad S5 by YOUNGJIN Korean Medicine Clinic
(2021)
Source URL:
First approved in 2021
Source:
Hepad S5 by YOUNGJIN Korean Medicine Clinic
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



Oxypaeoniflorin is a natural product derived from Radix Paeoniae Rubra and Radix Paeoniae Alba. Oxypaeoniflora had protective effects on AGEs-induced mesangial cell damage. The pretreatment with oxypaeoniflora (10-8-10-4 M) significantly increased advanced glycation end product-induced glutathione peroxidase and catalase activities in mesangial cells HBZY-1. Oxypaeniflora attenuated markedly advanced glycation end products-induced inflammation cytokines interleukin-6 and monocyte chemoattractant protein-1 levels in ELISA and western blot analysis in a dose-dependent manner. Oxypaeniflora was able to attenuate advanced glycation end products-induced oxidative damage and inflammation in mesangial cells. Oxypaeniflora might therefore have a beneficial effect in the treatment of diabetic nephropathy.