U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Showing 11 - 19 of 19 results

Status:
US Approved Rx (1988)
First approved in 1988

Class (Stereo):
CHEMICAL (ACHIRAL)



Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative. The following in vitro data are available, but their clinical significance is unknown. Naftifine has been shown to exhibit fungicidal activity in vitro against a br...
Status:
US Approved Rx (2016)
First approved in 1988

Class (Stereo):
CHEMICAL (ACHIRAL)



Oxiconazole nitrate is 2',4'-dichloro-2-imidazol-1-ylacetophenone (Z)-[0-(2,4-dichlorobenzyl)oxime], mononitrate is an imidazole derivative characterized by a broad fungistatic spectrum. In vitro oxiconazole is highly effective against many dermato...
Status:
US Approved Rx (2000)
First approved in 1981

Class (Stereo):
CHEMICAL (ABSOLUTE)



2S,4R ketoconazole or levoketoconazole is the 2S,4R enantiomer of ketoconazole, purified from racemic ketoconazole. Both enantiomers exerts antifungal activity. Ketoconazole activates AhR in gene reporter cell line and dose-dependently induces CYP1A1...
Status:
US Approved OTC
First approved in 1945

Class (Stereo):
CHEMICAL (ACHIRAL)



Undecylenic acid is unsaturated fatty acid, which naturally occurs in sweat, and is commercially produced by the vacuum distillation of castor bean oil. It is recognized as GRASE by FDA, and is marketed over the counter to treat skin infections and t...
Status:
US Approved OTC
First approved in 1945

Class (Stereo):
CHEMICAL (RACEMIC)



Undecylenic acid is unsaturated fatty acid, which naturally occurs in sweat, and is commercially produced by the vacuum distillation of castor bean oil. It is recognized as GRASE by FDA, and is marketed over the counter to treat skin infections and t...
Status:
US Approved OTC
First approved in 1945

Class (Stereo):
CHEMICAL (ACHIRAL)



Undecylenic acid is unsaturated fatty acid, which naturally occurs in sweat, and is commercially produced by the vacuum distillation of castor bean oil. It is recognized as GRASE by FDA, and is marketed over the counter to treat skin infections and t...
Status:
US Approved OTC
First approved in 1945

Class (Stereo):
CHEMICAL (ACHIRAL)



Undecylenic acid is unsaturated fatty acid, which naturally occurs in sweat, and is commercially produced by the vacuum distillation of castor bean oil. It is recognized as GRASE by FDA, and is marketed over the counter to treat skin infections and t...
Status:
US Approved OTC
First approved in 1945

Class (Stereo):
CHEMICAL (ACHIRAL)



Undecylenic acid is unsaturated fatty acid, which naturally occurs in sweat, and is commercially produced by the vacuum distillation of castor bean oil. It is recognized as GRASE by FDA, and is marketed over the counter to treat skin infections and t...
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (RACEMIC)



Eberconazole is an antifungal drug with broad antimicrobial spectrum of activity. The drug was developed and approved in Spain (Ebernet 1% cream) for the treatment of tinea. Eberconazole exerts fungicidal or fungistatic activity depending on concentr...

Showing 11 - 19 of 19 results