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Spinal cord disease

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1985

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Watersoluble, nephrotropic, low osmolar X-ray contrast media

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IOHEXOL

4419T9MX03

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Status:

US Approved Rx (1995)

First approved in 1985

Class (Stereo):

CHEMICAL (MIXED)

Targets:

vessels and anatomical structures

Conditions:

Spinal cord disease

Urinary system disease

Gastrointestinal disorders

Cardiovascular diseases

Iohexol is a nonionic, water-soluble radiographic contrast medium. Organic iodine compounds block x-rays as they pass through the body, thereby allowing body structures containing iodine to be delineated in contrast to those structures that do not co...

ntain iodine. It is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Drugs which lower seizure threshold, especially phenothiazine derivatives including those used for their antihistaminic or antinauseant properties, are not recommended for use with Iohexol. Others include monoamine oxidase (MAO) inhibitors, tricyclic antidepressants, CNS stimulants, psychoactive drugs described as analeptics, major tranquilizers, or antipsychotic drugs. The most frequently reported adverse reactions are headache, mild to moderate pain including backache, neckache and stiffness, nausea, and vomiting.

METRIZAMIDE

RHH3W8F1CO

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Status:

US Previously Marketed

First approved in 1978

Class (Stereo):

CHEMICAL (ABSOLUTE)

Conditions:

Spinal cord disease

Metrizamide is a glucosamine derivative of metrazoic acid, used as a contrast medium for myelography. Metrizamide is no longer marketed in the US.

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