U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Showing 1 - 10 of 18 results

Status:
US Approved Rx (2010)
First approved in 1986

Class (Stereo):
CHEMICAL (ABSOLUTE)



Aztreonam is the first monocyclic beta-lactam antibiotic (monobactam) originally isolated from Chromobacterium violaceum. Aztreonam has a high affinity for the protein-binding protein 3 (PBP-3) of aerobic gram-negative bacteria. Most of these organis...
Status:
US Approved Rx (2007)
First approved in 1985

Class (Stereo):
CHEMICAL (EPIMERIC-AXIAL)



Cefotetan is a semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positi...
Status:
US Previously Marketed
First approved in 1997

Class (Stereo):
CHEMICAL (ABSOLUTE)



Alatrofloxacin is a fluoroquinolone antibiotic developed as a mesylate salt and was sold under brand name Trovan, but was withdrawn from the U.S. market in 2001. Trovan was indicated for the treatment of patients initiating therapy in in-patient heal...
Status:
US Previously Marketed
First approved in 1989

Class (Stereo):
CHEMICAL (ABSOLUTE)



Cefmetazole is a semisynthetic cephamycin antibiotic. It has a broad spectrum of activity comparable to that of the second-generation cephalosporins, covering gram-positive, gram-negative, and anaerobic bacteria. Its bactericidal action results from ...
Status:
US Previously Marketed
First approved in 1981

Class (Stereo):
CHEMICAL (ABSOLUTE)



Cefotaxime sodium is a semisynthetic, broad spectrum cephalosporin antibiotic for parenteral administration. It’s a 3rd Generation Cephalosporin that is FDA approved for the treatment of lower respiratory tract infections, genitourinary infections, g...
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ABSOLUTE)



Sitafloxacin hydrate (DU-6859a, Gracevit), a new-generation, broad-spectrum oral fluoroquinolone that is very active against many Gram-positive, Gram-negative and anaerobic clinical isolates, including strains resistant to other fluoroquinolones, was...
Status:
US Approved Rx (2010)
First approved in 1986

Class (Stereo):
CHEMICAL (ABSOLUTE)



Aztreonam is the first monocyclic beta-lactam antibiotic (monobactam) originally isolated from Chromobacterium violaceum. Aztreonam has a high affinity for the protein-binding protein 3 (PBP-3) of aerobic gram-negative bacteria. Most of these organis...
Status:
US Approved Rx (2010)
First approved in 1986

Class (Stereo):
CHEMICAL (ABSOLUTE)



Aztreonam is the first monocyclic beta-lactam antibiotic (monobactam) originally isolated from Chromobacterium violaceum. Aztreonam has a high affinity for the protein-binding protein 3 (PBP-3) of aerobic gram-negative bacteria. Most of these organis...
Status:
US Approved Rx (2007)
First approved in 1985

Class (Stereo):
CHEMICAL (EPIMERIC)



Cefotetan is a semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positi...
Status:
US Previously Marketed
First approved in 1997

Class (Stereo):
CHEMICAL (ABSOLUTE)



Alatrofloxacin is a fluoroquinolone antibiotic developed as a mesylate salt and was sold under brand name Trovan, but was withdrawn from the U.S. market in 2001. Trovan was indicated for the treatment of patients initiating therapy in in-patient heal...

Showing 1 - 10 of 18 results