Showing 1 - 9 of 9 results
Class (Stereo):
CHEMICAL (ABSOLUTE)
Buprenorphine is an opioid analgesic, used to treat opioid addiction, moderate acute pain, and moderate chronic pain. Buprenorphine is a partial agonist at the mµ-opioid receptor and an antagonist at the kappa-opioid receptor. One unusual property o...
Class (Stereo):
CHEMICAL (ACHIRAL)
NMED-160 (also known as MK-6721, NP-118809, Z-160) is a potent N-type calcium channel blockers, which has good selectivity over L-type calcium channels. Neuromed Pharmaceuticals developed this compound for the treatment of the chronic pain. However, ...
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
PD-198306 is a cell-permeable, amino-benzamide derivative that acts as a potent and non-ATP-competitive inhibitor of MEK1/2 with an excellent selectivity over ERK, c-Src, Cdk's, and phosphatidylinositol 3-kinase γ. In vitro PD-198306 inhibits MEK act...
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
CP-96,345 is a potent, selective nonpeptide Substance P (NK1) receptor antagonist. Rather than being a primary neurotransmitter, it prolongs the nociception produced by other neurotransmitters. By controlling endothelial permeability, SP plays a majo...
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Palmidrol (palmitoylethanolamide, PEA) is a natural fatty acid amide found in a variety of foods, which was initially identified in egg yolk. It is an endogenous compound, locally synthesized in animal and human tissues and body fluids, to protect ag...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Buprenorphine is an opioid analgesic, used to treat opioid addiction, moderate acute pain, and moderate chronic pain. Buprenorphine is a partial agonist at the mµ-opioid receptor and an antagonist at the kappa-opioid receptor. One unusual property o...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Buprenorphine is an opioid analgesic, used to treat opioid addiction, moderate acute pain, and moderate chronic pain. Buprenorphine is a partial agonist at the mµ-opioid receptor and an antagonist at the kappa-opioid receptor. One unusual property o...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Buprenorphine is an opioid analgesic, used to treat opioid addiction, moderate acute pain, and moderate chronic pain. Buprenorphine is a partial agonist at the mµ-opioid receptor and an antagonist at the kappa-opioid receptor. One unusual property o...
Class (Stereo):
CHEMICAL (ACHIRAL)
NMED-160 (also known as MK-6721, NP-118809, Z-160) is a potent N-type calcium channel blockers, which has good selectivity over L-type calcium channels. Neuromed Pharmaceuticals developed this compound for the treatment of the chronic pain. However, ...