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Approval Year
Unknown
139,593
1921
1,467
2020
742
2013
596
2012
595
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Development Status
Other
121,663
Investigational
12,823
Possibly Marketed Outside US
4,339
Designated
448
Discontinued
139
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Primary Target
Dopamine D2 receptor
180
Serotonin 2a (5-HT2a) receptor
148
DNA
130
Dopamine transporter
120
Serotonin 1a (5-HT1a) receptor
119
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Highest Phase
Approved
1,802
Phase II
1,029
Phase III
516
Phase I
397
Not Provided
348
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Condition
Unknown
1,640
Cancer
425
Pain
275
Breast cancer
266
Hypertension
237
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Treatment Modality
Primary
4,823
Curative
581
Palliative
416
Preventing
368
Diagnostic
218
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CNS Activity
CNS Active
2,010
CNS Penetrant
715
CNS Non-penetrant
240
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Originator
Pfizer
246
GlaxoSmithKline
149
Eli Lilly
131
Novartis
105
Merck
98
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Substance Class
Chemical
100,439
Structurally Diverse
22,941
Protein
6,343
Concept
5,767
Mixture
2,082
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INN Stem
Chemical substance(-ine)
253
Monoclonal antibodies(-mab)
193
Tyrosine-kinase inhibitors(-tinib)
70
Peptides and glycopeptides(-tide)
68
Gene Therapy vectors(-vec)
63
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GInAS Tag
KEW
2,697
84371-57-3
1
ATN-3
1
PUBLIC DOMAIN RELEASE
1
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Code System
FDA UNII
132,914
CAS
100,603
PUBCHEM
98,100
EPA CompTox
67,161
ECHA (EC/EINECS)
27,761
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Protein Type
PEPTIDE
896
MONOCLONAL ANTIBODY
779
ENZYME
466
RECEPTOR
369
MONOCLONAL ANTIBODY CONJUGATE
120
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ATC Level 1
NERVOUS SYSTEM
184
CARDIOVASCULAR SYSTEM
176
ALIMENTARY TRACT AND METABOLISM
139
ANTIINFECTIVES FOR SYSTEMIC USE
116
RESPIRATORY SYSTEM
98
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ATC Level 2
ANTIBACTERIALS FOR SYSTEMIC USE
85
PSYCHOLEPTICS
75
CARDIAC THERAPY
61
PSYCHOANALEPTICS
51
ANTINEOPLASTIC AGENTS
45
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ATC Level 3
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
39
ANTIPSYCHOTICS
29
ANTIDEPRESSANTS
28
DRUGS FOR FUNCTIONAL BOWEL DISORDERS
28
HYPNOTICS AND SEDATIVES
28
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ATC Level 4
Benzodiazepine derivatives
21
Other cough suppressants
18
Other vasodilators used in cardiac diseases
16
Antiinflammatory preparations, non-steroids for topical use
15
Other psychostimulants and nootropics
15
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Substance Form
Principal Form
120,729
Salts, Hydrates, Esters, etc.
12,184
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Approval Year
Unknown
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ETHYL XIMENYNATE
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MEQ6O2FROG
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Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
Friluglanstat
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L65P4UM6KV
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Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
OLEOCANTHAL
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AC7QO6038O
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Status:
Investigational
Class (Stereo):
CHEMICAL (ABSOLUTE)
Labuxtinib
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QNX4G754W6
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Status:
Investigational
Class (Stereo):
CHEMICAL (ABSOLUTE)
Lerzeparib
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FA3YB8W7X9
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Status:
Investigational
Class (Stereo):
CHEMICAL (ABSOLUTE)
Uplarafenib
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TQU3V7CXC3
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Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
Irpagratinib
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X46B7JM4A8
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Status:
Investigational
Class (Stereo):
CHEMICAL (ABSOLUTE)
Aneratrigine
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6A5ZY5LT78
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Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
TYROSOL
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1AK4MU3SNX
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Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
Tibremciclib
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CRB7BT5JDQ
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Status:
Investigational
Class (Stereo):
CHEMICAL (ABSOLUTE)
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