U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 91 - 100 of 495 results

Status:
Possibly Marketed Outside US
Source:
Cellapy Haircell by Gm Holdings Co., Ltd
(2016)
Source URL:
First approved in 2016
Source:
Cellapy Haircell by Gm Holdings Co., Ltd
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Possibly Marketed Outside US
Source:
ZO MEDICAL RETINOL CREME Complex by ZO Skin Health, Inc.
(2016)
Source URL:
First approved in 2016
Source:
ZO MEDICAL RETINOL CREME Complex by ZO Skin Health, Inc.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

2-deoxyglucose is predominantly used as a diagnostic agent in its radiolabelled form (fluorine-18 is used as the radiolabel). Therapeutically, 2-deoxyglucose is an investigational drug that is being studied as an anticancer and antiviral agent. The exact mechanisms of action of 2-deoxyglucose is still being investigated, but it is known that in hypoxic cancer cells, 2-deoxyglucose is a glycolysis inhibitor that prevents ATP production and, ultimately, cell survival. With respect to antiviral therapy, 2-deoxyglucose was shown to be effective against herpes simplex virus by affecting the virus' ability to penetrate cells. As an experimental drug, 2-deoxyglucose was demonstrated to work as an anticonvulsant in temporal lobe epilepsy. In this condition, 2-deoxyglucose represses the expression of certain proteins that are at high levels after a seizure. Although there are several possible therapeutic indications for 2-deoxyglucose, presently there is no approved indication for 2-deoxyglucose as a therapeutic agent.
Status:
Possibly Marketed Outside US
Source:
The Barafu Intensive Serum by Bioresource Co., Ltd
(2016)
Source URL:
First approved in 2016
Source:
The Barafu Intensive Serum by Bioresource Co., Ltd
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)