U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 41 - 50 of 587 results

Status:
Possibly Marketed Outside US
Source:
NCT03996057: Phase 4 Interventional Withdrawn UTI
(2018)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



D-mannose is a simple sugar found naturally in fruits such as cranberries and pineapples. Unlike many sugars, it is not metabolised or stored in the liver. Much of it is excreted in the urine, where it interferes with particle attachment and prevents certain kind of bacteria from sticking to the walls and causing infection. Mannose supplement is also indicated for treatment of carbohydrate-deficient glycoprotein syndrome, however clinical trials failed to prove its efficacy.
Status:
Possibly Marketed Outside US
Source:
NCT04677712: Phase 4 Interventional Completed Edematous Fibrosclerotic Panniculopathy (EFP)
(2020)
Source URL:
First approved in 2011

Class (Stereo):
CHEMICAL (ABSOLUTE)

DB00144 (1-propionyl-2-butyl phosphatidylserine) is a phosphatidylserine derivative. It consists of a propionic and butyric acid residues attached in ester linkage to the first and second carbon of glycerol and serine attached through a phosphodiester linkage to the third carbon of the glycerol. DB00144 is not found in natural sources of phosphatidylserine, which contain fatty acids with a length of 20-22 carbon atoms. DB00144 was detected as one of the cellular metabolites in murine myocardium.
Status:
Possibly Marketed Outside US
Source:
ANTHELIOS by L'Oréal
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Conditions:

Dometrizole trisiloxane (Mexoryl XL®) is a lipophilic benzotriazole derivative used in sunscreen products to absorb ultraviolet (UV). It is a broadspectrum UVB/UVA filter with two peaks of absorption: one at 303 nm and the other one at 344 nm. Sunscreens containing dometrizole trisiloxane (Mexoryl XL®) are important in impeding UVA light, potentially reducing many of the characteristics of skin aging and preventing biochemical changes that can lead to nonmelanoma carcinoma. It has not yet been approved in the US, but has been available worldwide for many years in different sunscreens made by L'Oreal.
Status:
Possibly Marketed Outside US
Source:
Recover Lightening Complex with 4% Hydroquinone by The Skin Atelier, Inc.
(2011)
Source URL:
First approved in 2011
Source:
Recover Lightening Complex with 4% Hydroquinone by The Skin Atelier, Inc.
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Possibly Marketed Outside US
Source:
EnLyte by Jaymac Pharmaceuticals Llc
Source URL:
First approved in 2011

Class (Stereo):
CHEMICAL (ABSOLUTE)

Ferrous cysteine glycinate is a salt of glycine and cysteine salt iron (II). It is known as AminoFerr® and is used as a coloring agent and as an iron source in some multivitamins and supplements. According to information from the manufacturer, the chelating nature of aminoferr improves solubility and absorption of iron.