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Status:
US Previously Marketed
Source:
SOLAGE by ALMIRALL
(1999)
Source URL:
First approved in 1999
Source:
SOLAGE by ALMIRALL
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Mequinol (mequinol is 4-hydroxyanisole) is an active ingredient in topical drugs used for skin depigmentation. The mechanism of action of mequinol is unknown. Although mequinol is a substrate for the enzyme tyrosinase and acts as a competitive inhibitor of the formation of melanin precursors, the clinical significance of these findings is unknown.
Status:
Possibly Marketed Outside US
First approved in 1999
Source:
KeratexKNHD by Penleigh Irving Ltd
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Limonene is a naturally occurring chemical which is used in many food products, soaps and perfumes for its lemon-like flavor and odor. Limonene also is a registered active ingredient in 15 pesticide products used as insecticides, insect repellents, and dog and cat repellents. Pesticide products containing limonene are used for flea and tick control on pets, as an insecticide spray, an outdoor dog and cat repellent. It has also been used for relief of heartburn and gastroesophageal reflux (GERD). D-limonene has well-established chemopreventive activity against many types of cancer. Limonene and its oxidation products are skin and respiratory irritants.
Status:
Possibly Marketed Outside US
Source:
ANDA076498
(2017)
Source URL:
First approved in 1999
Source:
21 CFR 352
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Stearoxytrimethylsilane is classified as emollient and skin conditioning agent. It is used in a number of cosmetics formulations. It is derived from stearic acid, a fatty acid obtained from animal fat or plants. When derived from animals, it comes from cows, pigs, sheep, and according to Peta, from dogs and cats euthanized in shelters. Stearic acid is used in cosmetics and lubricants. DOWSIL™ 580 Wax (Stearoxytrimethylsilane (and) Stearyl Alcohol) is a soft, solid mixture of stearyl alcohol and stearoxy trimethylsilane. The cosmetic properties of the wax are a result of the silicone moiety. The inclusion of the stearoxy group involves compatibility with organic ingredients. Hair care and skin care products benefit from the property of this wax to facilitate the formation of a very thin film which is neither oily, tacky or too dry.
Status:
Possibly Marketed Outside US
Source:
21 CFR 352
(1999)
Source URL:
First approved in 1999
Source:
21 CFR 352
Source URL:
Class (Stereo):
CHEMICAL (MIXED)
Status:
Possibly Marketed Outside US
Source:
NADA141199
(1999)
Source URL:
First approved in 1999
Source:
NADA141199
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Glycocholic acid (GCA) is an important metabolite of bile acids, a conjugate of cholic acid with glycine. GCA urine levels are expected to be a specific diagnostic biomarker for hepatocellular carcinoma (HCC). The average GCA concentrations of HCC patients in plasma and urine were about 25 and 2.8 times than that of healthy volunteers.
Status:
Possibly Marketed Outside US
Source:
21 CFR 333A
(1999)
Source URL:
First approved in 1999
Source:
21 CFR 333A
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
Dermal-Soothe by Vetoquinol USA, Inc.
(1999)
Source URL:
First approved in 1999
Source:
Dermal-Soothe by Vetoquinol USA, Inc.
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
21 CFR 331
(2004)
Source URL:
First approved in 1999
Source:
ANDA074984
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Status:
Possibly Marketed Outside US
Source:
KeratexKHS by Penleigh Irving Ltd
(1999)
Source URL:
First approved in 1999
Source:
KeratexKHS by Penleigh Irving Ltd
Source URL:
Class (Stereo):
CHEMICAL (MIXED)
Status:
Possibly Marketed Outside US
Source:
21 CFR 352
(2014)
Source URL:
First approved in 1999
Source:
21 CFR 352
Source URL:
Class (Stereo):
CHEMICAL (MIXED)
