U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 101 - 110 of 129 results

Status:
US Previously Marketed
Source:
CAPSEBON by PITMAN MOORE
(1961)
Source URL:
First approved in 1958
Source:
Capsebon by Pitman-Moore (Dow Chem., USA)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Cadmium is a heavy metal that causes toxicity in humans and animals. Cadmium chloride is used due to its solubility in water and its ability to produce high concentrations of cadmium at the target site. Cadmium chloride is used in printing, photocopying, dyeing, analytical chemistry. Experiments on rodents have shown that this compound caused renal toxicity. Oxidative stress plays a key role in cadmium chloride-induced cyto/genotoxicity.
Status:
First approved in 1958
Source:
Suvren by Ayerst
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Conditions:

CAPTODIAME, also known as captodiamine, is a diphenylmethane derivative. It is a 5-HT2c receptor antagonist and agonist at sigma-1 and D3 dopamine receptors. It is an antihistamine which is used as a sedative and anxiolytic. CAPTODIAME is probably useful in preventing benzodiazepine withdrawal syndrome.
Status:
US Previously Marketed
Source:
CAPSEBON by PITMAN MOORE
(1961)
Source URL:
First approved in 1958
Source:
Capsebon by Pitman-Moore (Dow Chem., USA)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Cadmium is a heavy metal that causes toxicity in humans and animals. Cadmium chloride is used due to its solubility in water and its ability to produce high concentrations of cadmium at the target site. Cadmium chloride is used in printing, photocopying, dyeing, analytical chemistry. Experiments on rodents have shown that this compound caused renal toxicity. Oxidative stress plays a key role in cadmium chloride-induced cyto/genotoxicity.
Status:
US Previously Marketed
Source:
CAPSEBON by PITMAN MOORE
(1961)
Source URL:
First approved in 1958
Source:
Capsebon by Pitman-Moore (Dow Chem., USA)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Cadmium is a heavy metal that causes toxicity in humans and animals. Cadmium chloride is used due to its solubility in water and its ability to produce high concentrations of cadmium at the target site. Cadmium chloride is used in printing, photocopying, dyeing, analytical chemistry. Experiments on rodents have shown that this compound caused renal toxicity. Oxidative stress plays a key role in cadmium chloride-induced cyto/genotoxicity.
Status:
US Previously Marketed
Source:
Daricon by Pfizer
(1958)
Source URL:
First approved in 1958
Source:
Daricon by Pfizer
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Oxyphencyclimine is an anticholinergic drug (trade name Daricon) used in treating peptic ulcers. Daricon was discontinued in USA, but still used worldwide.
Status:
US Previously Marketed
Source:
CAPSEBON by PITMAN MOORE
(1961)
Source URL:
First approved in 1958
Source:
Capsebon by Pitman-Moore (Dow Chem., USA)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Cadmium is a heavy metal that causes toxicity in humans and animals. Cadmium chloride is used due to its solubility in water and its ability to produce high concentrations of cadmium at the target site. Cadmium chloride is used in printing, photocopying, dyeing, analytical chemistry. Experiments on rodents have shown that this compound caused renal toxicity. Oxidative stress plays a key role in cadmium chloride-induced cyto/genotoxicity.
Status:
US Previously Marketed
Source:
CAPSEBON by PITMAN MOORE
(1961)
Source URL:
First approved in 1958
Source:
Capsebon by Pitman-Moore (Dow Chem., USA)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Cadmium is a heavy metal that causes toxicity in humans and animals. Cadmium chloride is used due to its solubility in water and its ability to produce high concentrations of cadmium at the target site. Cadmium chloride is used in printing, photocopying, dyeing, analytical chemistry. Experiments on rodents have shown that this compound caused renal toxicity. Oxidative stress plays a key role in cadmium chloride-induced cyto/genotoxicity.
Status:
US Previously Marketed
Source:
CAPSEBON by PITMAN MOORE
(1961)
Source URL:
First approved in 1958
Source:
Capsebon by Pitman-Moore (Dow Chem., USA)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Cadmium is a heavy metal that causes toxicity in humans and animals. Cadmium chloride is used due to its solubility in water and its ability to produce high concentrations of cadmium at the target site. Cadmium chloride is used in printing, photocopying, dyeing, analytical chemistry. Experiments on rodents have shown that this compound caused renal toxicity. Oxidative stress plays a key role in cadmium chloride-induced cyto/genotoxicity.
Status:
US Previously Marketed
First approved in 1958
Source:
Madribon by Hoffmann-La Roche
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Sulfadimethoxine is a sulfonamide antibacterial used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections. It is most frequently used in veterinary medicine, although it is approved in some countries for use in humans. Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic acid) from para-aminobenzoic acid. Sulfadimethoxine is approved in Russia for use in humans, including children, and has been successfully used there for more than 35 years and is available as an over-the-counter drug manufactured by a number of Russian pharmaceutical companies. In USA and Europe sulfadimethoxine is approved in a veterinary medicinal products. ANADA was approved by FDA in US in 1997 as an Over the Counter medicine for treatment of bovine respiratory disease complex (shipping fever complex) and bacterial pneumonia associated with Pasteurella Spp. Sensitive to sulfadimethoxine; necrotic pododermatitis (foot rot) and calf diphtheria caused by Fusobacterium necrophorum (Sphaerophorus necrophorus) sensitive to sulfadimethoxine. Bioequivalence for this generic animal drug, Sulfadimethoxine Injection 40%, was established by demonstration of chemical equivalence to the pioneer product, Hoffmann-La Roche's Albon® Injection 40% (NADA 041-245).
Status:
US Previously Marketed
First approved in 1958

Class (Stereo):
CHEMICAL (ABSOLUTE)

Showing 101 - 110 of 129 results