U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 2CHO2.Zn
Molecular Weight 155.444
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ZINC FORMATE

SMILES

[Zn++].[O-]C=O.[O-]C=O

InChI

InChIKey=XOBMCBQSUCOAOC-UHFFFAOYSA-L
InChI=1S/2CH2O2.Zn/c2*2-1-3;/h2*1H,(H,2,3);/q;;+2/p-2

HIDE SMILES / InChI

Molecular Formula CHO2
Molecular Weight 45.0174
Charge -1
Count
MOL RATIO 2 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Zn
Molecular Weight 65.409
Charge 2
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Zinc formate is a white crystalline solid. It is soluble in water. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. It is used as a catalyst in chemical processing and as a waterproofing agent. Zinc formate is used as a pharmaceutical intermediate. Synthetic and plant-derived zinc formate were equally effective as inhibitors of cytochrome P-450 enzymes and as hepatoprotective agents in carbon tetrachloride-treated rats.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

PubMed

Sample Use Guides

In Vivo Use Guide
Rats: Groups of 3 rats were administered 1 ml of water or 10 mg/ml zinc formate solution daily by gastric lavage for 3 days.
Route of Administration: Other
In Vitro Use Guide
Zinc formate (0.25 - 2.50 mg/ml) dose-dependently inhibited rat liver microsomal aminopyrine-N-demethylase activity.
Substance Class Chemical
Record UNII
ZZ67G2CT75
Record Status Validated (UNII)
Record Version