U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Wed Apr 02 19:16:43 GMT 2025
Edited
by admin
on Wed Apr 02 19:16:43 GMT 2025
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State Self-inactivating, non-replicating
Organism Family Retroviridae
Organism Genus Lentivirus
Organism Species human immunodeficiency virus 1
Infraspecific Type RECOMBINANT VECTOR
Infraspecific Name Soficabtagene geleucel LV (HCAR7)
Part WHOLE
Record UNII
ZY2QR8ZJZ5
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Soficabtagene geleucel lentiviral vector encoding a chimeric antigen receptor (CAR) targeting CD7
Preferred Name English
Soficabtagene geleucel lentiviral vector
Common Name English
Code System Code Type Description
FDA UNII
ZY2QR8ZJZ5
Created by admin on Wed Apr 02 19:16:43 GMT 2025 , Edited by admin on Wed Apr 02 19:16:43 GMT 2025
PRIMARY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
INSERTED GENE EXPRESSION VECTOR Soficabtagene geleucel transgene insert encoding anti-CD7 CAR KBJ527FP3Z