Sterol O-acyltransferase 1

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 14:23:40 GMT 2025` Edited by `admin` on `Wed Apr 02 14:23:40 GMT 2025`
Protein Type	ENZYME
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	ZX7XK4NS7A
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Acyl-coenzyme A:cholesterol acyltransferase 1

Preferred Name

English

Sterol O-acyltransferase 1

Common Name

English

Cholesterol acyltransferase 1

Common Name

English

Acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT-1)

Common Name

English

SOAT1

Common Name

English

Code System Code Type Description

UNIPROT

P35610

Created by admin on Wed Apr 02 14:23:40 GMT 2025 , Edited by admin on Wed Apr 02 14:23:40 GMT 2025

PRIMARY

FDA UNII

ZX7XK4NS7A

Created by admin on Wed Apr 02 14:23:40 GMT 2025 , Edited by admin on Wed Apr 02 14:23:40 GMT 2025

PRIMARY

From	To
4_528	4_546
3_528	3_546
2_528	2_546
1_528	1_546

Related Record Type Details


					3DK1X2C37M

EFLUCIMIBE

INHIBITOR -> TARGET

Amount:


					28LQ20T5RC

AVASIMIBE

INHIBITOR -> TARGET

Amount:


					D874R9PZ9T

PACTIMIBE

INHIBITOR -> TARGET

Amount:


					VK9OS8R205

NEVANIMIBE

TARGET -> INHIBITOR

Amount:


					2GG0K1I5CI

CANOSIMIBE

INHIBITOR -> TARGET

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1] [3_1] [4_1]	N-TERMINUS	M		N-ACETYLMETHIONINE	9J12WX5B6A
AMINO_ACID_SUBSTITUTION	[1_8] [2_8] [3_8] [4_8]	SITE_SPECIFIC	S		DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL