Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | 2C4H9N3O2.C4H6O4 |
| Molecular Weight | 380.3544 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)CCC(O)=O.NC(=N)NCCC(O)=O.NC(=N)NCCC(O)=O
InChI
InChIKey=BLZFAXMHFJUYRF-UHFFFAOYSA-N
InChI=1S/2C4H9N3O2.C4H6O4/c2*5-4(6)7-2-1-3(8)9;5-3(6)1-2-4(7)8/h2*1-2H2,(H,8,9)(H4,5,6,7);1-2H2,(H,5,6)(H,7,8)
| Molecular Formula | C4H9N3O2 |
| Molecular Weight | 131.1332 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C4H6O4 |
| Molecular Weight | 118.088 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Mitochondrial intermembrane inclusion bodies: the common denominator between human mitochondrial myopathies and creatine depletion, due to impairment of cellular energetics. | 1997 Sep |
|
| Synthesis and biological activity of aminoguanidine and diaminoguanidine analogues of the antidiabetic/antiobesity agent 3-guanidinopropionic acid. | 2001 Apr 12 |
|
| Influence of 72% injury in one kidney on several organs involved in guanidino compound metabolism: a time course study. | 2001 Jul |
|
| AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation. | 2002 Dec 10 |
|
| Dehydration modifies guanidino compound concentrations in the different zones of the rat kidney. | 2002 May |
|
| Effects of creatine loading and depletion on rat skeletal muscle contraction. | 2002 Oct |
|
| A role for guanidino compounds in the brain. | 2003 Feb |
|
| Creatine transporter activity and content in the rat heart supplemented by and depleted of creatine. | 2003 Feb |
|
| Stimulation of HSP72 expression following ATP depletion and short-term exercise training in fast-twitch muscle. | 2004 Jan |
|
| Pseudomonas aeruginosa PAO1 genes for 3-guanidinopropionate and 4-guanidinobutyrate utilization may be derived from a common ancestor. | 2005 Dec |
|
| Electrolysis stimulates creatine transport and transporter cell surface expression in incubated mouse skeletal muscle: potential role of ROS. | 2006 Dec |
|
| Possible role of creatine concentrations in the brain in regulating appetite and weight. | 2006 Jul 26 |
|
| Increased resistance to fatigue in creatine kinase deficient muscle is not due to improved contractile economy. | 2006 Jun |
|
| In vivo effects of myocardial creatine depletion on left ventricular function, morphology, and energy metabolism--consequences in acute myocardial infarction. | 2007 Apr |
|
| Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis. | 2007 Feb |
|
| BVT.3531 reduces body weight and activates K(ATP) channels in isolated arcuate neurons in rats. | 2007 Jun 7 |
|
| Ontogeny up-regulates renal Na(+)/Cl(-)/creatine transporter in rat. | 2007 Nov |
|
| Arginine and glycine stimulate creatine synthesis in creatine transporter 1-deficient lymphoblasts. | 2008 Apr 1 |
|
| [Effects of creatine phosphokinase competitive inhibitor on system and tissue energy metabolism in rats in the norm and during unloading]. | 2008 Jul-Aug |
|
| Accumulation of methylguanidine and changes in guanidino compound levels in plasma, urine, and kidneys of furosemide-treated rats. | 2008 Jun |
|
| Decreasing intramuscular phosphagen content simultaneously increases plasma membrane FAT/CD36 and GLUT4 transporter abundance. | 2008 Sep |
|
| Muscle-specific differences in the response of mitochondrial proteins to beta-GPA feeding: an evaluation of potential mechanisms. | 2009 Jun |
|
| The orally active antihyperglycemic drug beta-guanidinopropionic acid is transported by the human proton-coupled amino acid transporter hPAT1. | 2009 May-Jun |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 14:23:51 GMT 2023
by
admin
on
Sat Dec 16 14:23:51 GMT 2023
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| Record UNII |
ZTT3AXT4KC
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| Record Status |
Validated (UNII)
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| Record Version |
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ZTT3AXT4KC
Created by
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2106793-65-9
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LM-163
Created by
admin on Sat Dec 16 14:23:51 GMT 2023 , Edited by admin on Sat Dec 16 14:23:51 GMT 2023
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