ALLOPREGNANE

CC[C@H]1CC[C@H]2[C@@H]3CC[C@H]4CCCC[C@]4(C)[C@H]3CC[C@]12C

InChIKey=JWMFYGXQPXQEEM-GCOKGBOCSA-N

InChI=1S/C21H36/c1-4-15-9-11-18-17-10-8-16-7-5-6-13-20(16,2)19(17)12-14-21(15,18)3/h15-19H,4-14H2,1-3H3/t15-,16+,17-,18-,19-,20-,21+/m0/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	7 / 7
E/Z Centers	0
Optical Activity	UNSPECIFIED

PubMed

Title	Date	PubMed
Antagonism of neurosteroid modulation of native gamma-aminobutyric acid receptors by (3alpha,5alpha)-17-phenylandrost-16-en-3-ol.	2007-10-31	17658511
3Beta-hydroxysteroids and pregnenolone sulfate inhibit recombinant rat GABA(A) receptor through different channel property.	2007-02-28	17239367
Progesterone metabolites in breast cancer.	2006-09	16954427
The role of progesterone metabolites in breast cancer: potential for new diagnostics and therapeutics.	2005-02	15860263
Thymol, a constituent of thyme essential oil, is a positive allosteric modulator of human GABA(A) receptors and a homo-oligomeric GABA receptor from Drosophila melanogaster.	2003-12	14623762
Changes in 5alpha-pregnane steroids and neurosteroidogenic enzyme expression in fetal sheep with umbilicoplacental embolization.	2003-12	12930920
Changes in 5alpha-pregnane steroids and neurosteroidogenic enzyme expression in the perinatal sheep.	2003-06	12646725
Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties.	2003-02	12510009

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:55:28 GMT 2025` Edited by `admin` on `Mon Mar 31 21:55:28 GMT 2025`
Record UNII	ZTF5KN7S9R
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

ALLOPREGNANE [MI]

Preferred Name

English

ALLOPREGNANE

Common Name

English

PREGNANE, (5.ALPHA.)-

Systematic Name

English

5.ALPHA.-PREGNANE

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID201031678