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Details

Stereochemistry ABSOLUTE
Molecular Formula C19H24N2O4
Molecular Weight 344.4049
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of N-(2-HYDROXY-5-((1S)-1-HYDROXY-2-(((1R)-2-(4-METHOXYPHENYL)-1-METHYLETHYL)AMINO)ETHYL)PHENYL)FORMAMIDE

SMILES

COC1=CC=C(C[C@@H](C)NC[C@@H](O)C2=CC=C(O)C(NC=O)=C2)C=C1

InChI

InChIKey=BPZSYCZIITTYBL-BFUOFWGJSA-N
InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22)/t13-,19-/m1/s1

HIDE SMILES / InChI

Molecular Formula C19H24N2O4
Molecular Weight 344.4049
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Economic evaluation of BDP/formoterol fixed vs two single inhalers in asthma treatment.
2010-09
Mitochondrial respiratory chain dysfunction in dorsal root ganglia of streptozotocin-induced diabetic rats and its correction by insulin treatment.
2010-04
Modification of superoxide dismutase 1 (SOD1) properties by a GFP tag--implications for research into amyotrophic lateral sclerosis (ALS).
2010-03-08
Antioxidant enzymes and lipid peroxidation in endometrium of patients with polyps, myoma, hyperplasia and adenocarcinoma.
2009-12-23
The synthetic inhibitor of fibroblast growth factor receptor PD166866 controls negatively the growth of tumor cells in culture.
2009-12-11
Effects of chromium picolinate on glycemic control and kidney of the obese Zucker rat.
2009-12-10
Nebulized formoterol provides added benefits to tiotropium treatment in chronic obstructive pulmonary disease.
2009-11
Safety and efficacy of oral DMSA therapy for children with autism spectrum disorders: Part A--medical results.
2009-10-23
Human papillomavirus-16 E7 interacts with glutathione S-transferase P1 and enhances its role in cell survival.
2009-10-13
Freeze-dried strawberry powder improves lipid profile and lipid peroxidation in women with metabolic syndrome: baseline and post intervention effects.
2009-09-28
Dexrazoxane-afforded protection against chronic anthracycline cardiotoxicity in vivo: effective rescue of cardiomyocytes from apoptotic cell death.
2009-09-01
Use of formoterol in the treatment of stuttering. A pilot study.
2009-09
Basic study on active changes in biological function of mouse liver graft in cold storage after low-dose x-irradiation.
2009-09
Reduction of lipoxidative load by secretory phospholipase A2 inhibition protects against neurovascular injury following experimental stroke in rat.
2009-08-13
Dimethylarginine dimethylaminohydrolase in rat penile tissue: reduced enzyme activity is responsible for erectile dysfunction in a rat model of atherosclerosis.
2009-07-16
Efficacy and safety of nebulized formoterol as add-on therapy in COPD patients receiving maintenance tiotropium bromide: Results from a 6-week, randomized, placebo-controlled, clinical trial.
2009-06-18
Beneficial Effects of Fermented Green Tea Extract in a Rat Model of Non-alcoholic Steatohepatitis.
2009-05
Inhaled corticosteroid therapy for patients with persistent asthma: learnings from studies of inhaled budesonide.
2009-04-07
Methodological challenges in online trials.
2009-04-03
In vitro deposition properties of nebulized formoterol fumarate: effect of nebulization time, airflow, volume of fill and nebulizer type.
2009-04
IGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigation.
2009-03-02
Nebulized formoterol effect on bronchodilation and satisfaction in COPD patients compared to QID ipratropium/albuterol MDI.
2009-03
Spray drying of budesonide, formoterol fumarate and their composites-II. Statistical factorial design and in vitro deposition properties.
2009-02-09
Spray drying of budesonide, formoterol fumarate and their composites--I. Physicochemical characterisation.
2009-02-09
Hyperbaric oxygen treatment improves GFR in rats with ischaemia/reperfusion renal injury: a possible role for the antioxidant/oxidant balance in the ischaemic kidney.
2009-02
[The effect of tobacco smoking on nitric oxide serum concentration in pregnant women and umbilical cord blood].
2009
LAS0811: from combinatorial chemistry to activation of antioxidant response element.
2009
Ceruloplasmin and superoxide dismutase (SOD1) in heterozygotes for Wilson disease: A case control study.
2009
Probiotics prevent intestinal barrier dysfunction in acute pancreatitis in rats via induction of ileal mucosal glutathione biosynthesis.
2009
Targeted induction of lung endothelial cell apoptosis causes emphysema-like changes in the mouse.
2008-10-24
Equivalence of a single saline nebulised dose of formoterol powder vs three doses of nebulised Albuterol every twenty minutes in acute asthma in children: a suitable cost effective approach for developing nations.
2008-10-22
Compatibility and aerosol characteristics of formoterol fumarate mixed with other nebulizing solutions.
2008-10
Nebulized formoterol fumarate: Dose selection and pharmacokinetics.
2008-10
Long-term safety of nebulized formoterol: results of a twelve-month open-label clinical trial.
2008-08
Inhaled corticosteroids and long-acting beta-agonists in adult asthma: a winning combination in all?
2008-08
Mitogenic and functional responses by nicotine and hydrogen peroxide in AR42J cells: a comparative study.
2008-07-31
No Different Sensitivity in Terms of Whole-Body Irradiation between Normal and Acatalasemic Mice.
2008-07
RAGE and modulation of ischemic injury in the diabetic myocardium.
2008-07
Short inhalation exposures of the isolated and perfused rat lung to respirable dry particle aerosols; the detailed pharmacokinetics of budesonide, formoterol, and terbutaline.
2008-06
Systematic review and economic analysis of the comparative effectiveness of different inhaled corticosteroids and their usage with long-acting beta2 agonists for the treatment of chronic asthma in children under the age of 12 years.
2008-05
Formoterol fumarate and roxithromycin effects on muscle mass in an animal model of cancer cachexia.
2008-05
Increased mitochondrial DNA damage and down-regulation of DNA repair enzymes in aged rodent retinal pigment epithelium and choroid.
2008-04-04
New approaches to managing asthma: a US perspective.
2008-04
Effect of 17beta-estradiol on olfactory bulbectomy-induced oxidative stress and behavioral changes in rats.
2008-04
Concomitant treatment with nebulized formoterol and tiotropium in subjects with COPD: a placebo-controlled trial.
2008-04
Efficacy and safety of formoterol fumarate delivered by nebulization to COPD patients.
2008-02
Formoterol fumarate inhalation powder vs albuterol nebulizer for the treatment of asthma in the acute care setting.
2008-02
The role of particulate matter-associated zinc in cardiac injury in rats.
2008-01
Effect of Docosahexaenoic Acid Ingestion on Temporal Change in Urinary Excretion of Mercapturic Acid in ODS Rats.
2007-11
Total antioxidant status and 8-hydroxy-2'-deoxyguanosine levels in gingival and peripheral blood of periodontitis patients.
2007-03-07
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:30:50 GMT 2025
Edited
by admin
on Mon Mar 31 21:30:50 GMT 2025
Record UNII
ZP145530CI
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FORMAMIDE, N-(2-HYDROXY-5-(1-HYDROXY-2-((2-(4-METHOXYPHENYL)-1-METHYLETHYL)AMINO)ETHYL)PHENYL)-, (S-(R*,S*))-
Preferred Name English
N-(2-HYDROXY-5-((1S)-1-HYDROXY-2-(((1R)-2-(4-METHOXYPHENYL)-1-METHYLETHYL)AMINO)ETHYL)PHENYL)FORMAMIDE
Systematic Name English
FORMAMIDE, N-(2-HYDROXY-5-((1S)-1-HYDROXY-2-(((1R)-2-(4-METHOXYPHENYL)-1-METHYLETHYL)AMINO)ETHYL)PHENYL)-
Systematic Name English
Code System Code Type Description
PUBCHEM
9862958
Created by admin on Mon Mar 31 21:30:50 GMT 2025 , Edited by admin on Mon Mar 31 21:30:50 GMT 2025
PRIMARY
CAS
67346-50-3
Created by admin on Mon Mar 31 21:30:50 GMT 2025 , Edited by admin on Mon Mar 31 21:30:50 GMT 2025
PRIMARY
EPA CompTox
DTXSID90217701
Created by admin on Mon Mar 31 21:30:50 GMT 2025 , Edited by admin on Mon Mar 31 21:30:50 GMT 2025
PRIMARY
FDA UNII
ZP145530CI
Created by admin on Mon Mar 31 21:30:50 GMT 2025 , Edited by admin on Mon Mar 31 21:30:50 GMT 2025
PRIMARY