Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 12:26:06 GMT 2023
by
admin
on
Sat Dec 16 12:26:06 GMT 2023
|
| Protein Sub Type | |
| Sequence Type | COMPLETE |
| Record UNII |
ZHQ2R96QPT
|
| Record Status |
Validated (UNII)
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| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Systematic Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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P31639
Created by
admin on Sat Dec 16 12:26:08 GMT 2023 , Edited by admin on Sat Dec 16 12:26:08 GMT 2023
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PRIMARY | |||
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SGLT2
Created by
admin on Sat Dec 16 12:26:08 GMT 2023 , Edited by admin on Sat Dec 16 12:26:08 GMT 2023
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PRIMARY | |||
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ZHQ2R96QPT
Created by
admin on Sat Dec 16 12:26:08 GMT 2023 , Edited by admin on Sat Dec 16 12:26:08 GMT 2023
|
PRIMARY | |||
|
P31639
Created by
admin on Sat Dec 16 12:26:08 GMT 2023 , Edited by admin on Sat Dec 16 12:26:08 GMT 2023
|
PRIMARY | |||
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335197-46-1
Created by
admin on Sat Dec 16 12:26:08 GMT 2023 , Edited by admin on Sat Dec 16 12:26:08 GMT 2023
|
PRIMARY |
| Glycosylation Type | HUMAN |
| Glycosylation Link Type | Site |
|---|---|
| N | 1_250 |
| N | 1_399 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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INHIBITOR -> TRANSPORTER | |||
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INHIBITOR -> TARGET |
COMPETITIVE INHIBITOR
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
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SUBSTRATE -> TRANSPORTER |
90% of the glucose that is initially filtered is reabsorbed by a high capacity system controlled by SGLT-2 in the early convoluted segment of the proximal tubules
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
CHO CELLS STABLY EXPRESSING HUMAN SGLT2, MEASURING THE SODIUM DEPENDENT UPTAKE OF 14C-LABELED METHYL-ALPHA-D-GLUCOPYRANOSIDE (AMG) (N=10)
INHIBITOR
IC50
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET | |||
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RADIOLIGAND->TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT:NUMBER AVERAGE(CALCULATED) | CHEMICAL |
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