U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Thu Jul 06 18:00:08 UTC 2023
Edited
by admin
on Thu Jul 06 18:00:08 UTC 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
ZHQ2R96QPT
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM/GLUCOSE COTRANSPORTER 2
Common Name English
NA(+)/GLUCOSE COTRANSPORTER 2
Common Name English
LOW AFFINITY SODIUM-GLUCOSE COTRANSPORTER
Common Name English
SODIUM/GLUCOSE COTRANSPORTER 2 HUMAN
Common Name English
SODIUM-DEPENDENT GLUCOSE CO-TRANSPORTER 2
Common Name English
SODIUM/GLUCOSE COTRANSPORTER 2 (HUMAN)
Common Name English
SGLT2
Common Name English
SLC5A2
Common Name English
SOLUTE CARRIER FAMILY 5 MEMBER 2
Systematic Name English
SODIUM-GLUCOSE CO-TRANSPORTER 2
Common Name English
Code System Code Type Description
PHAROS
P31639
Created by admin on Thu Jul 06 18:00:09 UTC 2023 , Edited by admin on Thu Jul 06 18:00:09 UTC 2023
PRIMARY
WIKIPEDIA
SGLT2
Created by admin on Thu Jul 06 18:00:09 UTC 2023 , Edited by admin on Thu Jul 06 18:00:09 UTC 2023
PRIMARY
FDA UNII
ZHQ2R96QPT
Created by admin on Thu Jul 06 18:00:09 UTC 2023 , Edited by admin on Thu Jul 06 18:00:09 UTC 2023
PRIMARY
UNIPROT
P31639
Created by admin on Thu Jul 06 18:00:09 UTC 2023 , Edited by admin on Thu Jul 06 18:00:09 UTC 2023
PRIMARY
CAS
335197-46-1
Created by admin on Thu Jul 06 18:00:09 UTC 2023 , Edited by admin on Thu Jul 06 18:00:09 UTC 2023
PRIMARY
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_250
N 1_399
Related Record Type Details
INHIBITOR -> TRANSPORTER
INHIBITOR -> TARGET
COMPETITIVE INHIBITOR
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
SUBSTRATE -> TRANSPORTER
90% of the glucose that is initially filtered is reabsorbed by a high capacity system controlled by SGLT-2 in the early convoluted segment of the proximal tubules
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
CHO CELLS STABLY EXPRESSING HUMAN SGLT2, MEASURING THE SODIUM DEPENDENT UPTAKE OF 14C-LABELED METHYL-ALPHA-D-GLUCOPYRANOSIDE (AMG) (N=10)
INHIBITOR
IC50
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
RADIOLIGAND->TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED) CHEMICAL