Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C5H12 |
| Molecular Weight | 72.1488 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCC(C)C
InChI
InChIKey=QWTDNUCVQCZILF-UHFFFAOYSA-N
InChI=1S/C5H12/c1-4-5(2)3/h5H,4H2,1-3H3
| Molecular Formula | C5H12 |
| Molecular Weight | 72.1488 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Isopentane is a colorless liquid with an alcohol or gasoline-like odor. It is used as a solvent, and as a blowing agent in making plastics. Inhalation can cause dizziness, drowsiness, headache, and unconsciousness. Skin exposure leads to dry skin. Ingestion can cause nausea and vomiting. Isopentane is an aspiration hazard. If swallowed the substance easily enters the airways and could result in aspiration pneumonitis. Isopentane causes CNS depression between 270 and 400 mg/L, and is a weak cardiac sensitizer. Isopentane is an excipient. In cosmetics and personal care products, Isopentane is used in the formulation of shaving cream, cleansing products, hair conditioners, and makeup. Isopentane is a component of Ralgex Freeze Spray, which is used for the symptomatic relief of muscular pain and stiffness, including backache, sciatica, lumbago, fibrositis, rheumatic pain. Ralgex Freeze Spray contains Glycol Monosalicylate 10% w/w, Methoxymethane 14.41% w/w and Isopentane 67.77% w/w. Ralgex Freeze Spray is also used for the symptomatic relief of sprains, strains and bruises associated with sports injuries, and stiffness following sporting exercise.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Ascites induces modulation of alpha6beta1 integrin and urokinase plasminogen activator receptor expression and associated functions in ovarian carcinoma. | 2005-04-25 |
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| Hyperosmotic stimulus induces reversible angiogenesis within the hypothalamic magnocellular nuclei of the adult rat: a potential role for neuronal vascular endothelial growth factor. | 2005-03-24 |
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| The absence of reactive oxygen species production protects mice against bleomycin-induced pulmonary fibrosis. | 2005-01-21 |
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| Claudin 7 expression and localization in the normal murine mammary gland and murine mammary tumors. | 2005 |
|
| Chemokine receptors in the rheumatoid synovium: upregulation of CXCR5. | 2005 |
|
| Combination of histopathological and electromyographic patterns can help to evaluate functional outcome of critical ill patients with neuromuscular weakness syndromes. | 2004-12 |
|
| Evaluation of hypoxia in an experimental rat tumour model by [(18)F]fluoromisonidazole PET and immunohistochemistry. | 2004-11-29 |
|
| Nodular osteochondrogenic activity in soft tissue surrounding osteoma in neurogenic para osteo-arthropathy: morphological and immunohistochemical study. | 2004-11-25 |
|
| Chirality control in optically active polysilane aggregates. | 2004-10-27 |
|
| A new rearrangement process in tert-amyl cation. | 2004-10-27 |
|
| Cholesterol is essential for mitosis progression and its deficiency induces polyploid cell formation. | 2004-10-15 |
|
| Isoamyl alcohol-induced morphological change in Saccharomyces cerevisiae involves increases in mitochondria and cell wall chitin content. | 2004-10 |
|
| Localization of ABCG5 and ABCG8 proteins in human liver, gall bladder and intestine. | 2004-09-21 |
|
| Comparison in gene expression of secretory human endometrium using laser microdissection. | 2004-09-17 |
|
| Plasticity of histamine H3 receptor expression and binding in the vestibular nuclei after labyrinthectomy in rat. | 2004-09-10 |
|
| Determination of key odorant compounds in freshly distilled cognac using GC-O, GC-MS, and sensory evaluation. | 2004-09-08 |
|
| Synthesis of flavor and fragrance esters using Candida antarctica lipase. | 2004-09 |
|
| The state of the iron promoter in tungstated zirconia catalysts. | 2004-08-20 |
|
| Gene expression variation between mouse inbred strains. | 2004-08-18 |
|
| A high-throughput approach to lanthanide complexes and their rapid screening in the ring opening polymerisation of caprolactone. | 2004-08-07 |
|
| Controlled production of Camembert-type cheeses. Part II. Changes in the concentration of the more volatile compounds. | 2004-08 |
|
| Calcineurin activation influences muscle phenotype in a muscle-specific fashion. | 2004-07-28 |
|
| The relationship between volatile organic profiles and emission sources in ozone episode region-a case study in Southern Taiwan. | 2004-07-26 |
|
| Assessment of vascular reactivity in rat brain glioma by measuring regional blood volume during graded hypoxic hypoxia. | 2004-07-19 |
|
| Off-vine grape drying effect on volatile compounds and aromatic series in must from Pedro Ximénez grape variety. | 2004-06-16 |
|
| Lipopolysaccharide induces nitric oxide synthase expression and platelet-activating factor increases nitric oxide production in human fetal membranes in culture. | 2004-06-10 |
|
| Use of an ionic liquid in a two-phase system to improve an alcohol dehydrogenase catalysed reduction. | 2004-05-07 |
|
| Isoamylcobalamin-acetone-water (1/0.385/12.650). | 2004-04 |
|
| Expression and localization of nuclear proteins in autosomal-dominant Emery-Dreifuss muscular dystrophy with LMNA R377H mutation. | 2004-03-30 |
|
| Inertial solvent dynamics and the analysis of spectral line shapes: Temperature-dependent absorption spectrum of beta-carotene in nonpolar solvent. | 2004-03-01 |
|
| Early segmental changes in ischemic acute tubular necrosis of the rat kidney. | 2004-03 |
|
| Therapeutic potential of monoisoamyl and monomethyl esters of meso 2,3-dimercaptosuccinic acid in gallium arsenide intoxicated rats. | 2004-02-15 |
|
| Rhodococcus aetherivorans sp. nov., a new species that contains methyl t-butyl ether-degrading actinomycetes. | 2004-02 |
|
| Got milk? A pheromonal message for newborn rabbits. | 2004-01 |
|
| Reversal of cadmium induced oxidative stress by chelating agent, antioxidant or their combination in rat. | 2003-12-10 |
|
| Insulin-like growth factor-1 protects ischemic murine myocardium from ischemia/reperfusion associated injury. | 2003-12 |
|
| [Mitochondriopathies]. | 2003-11-01 |
|
| Analysis of natural gas: the necessity of multiple standards for calibration. | 2003-10-31 |
|
| Serial pathways from primate prefrontal cortex to autonomic areas may influence emotional expression. | 2003-10-10 |
|
| Increased brain histamine H3 receptor expression during hibernation in golden-mantled ground squirrels. | 2003-09-24 |
|
| [Histochemical study of the sensory endings of muscle spindles in rat longissimus muscles]. | 2003-08 |
|
| Examination of murine tear film. | 2003-08 |
|
| n-Pentane and isopentane in one-dimensional channels. | 2003-06-18 |
|
| Mechanism of the first-order phase transition of an acylurea derivative: observation of intermediate stages of transformation with a detailed temperature-resolved single-crystal diffraction method. | 2003-06 |
|
| Presence of opioid growth factor and its receptor in the normal dog, cat and horse cornea. | 2003-06 |
|
| Volatile organic profiles and photochemical potentials from motorcycle engine exhaust. | 2003-05 |
|
| Structure-activity relationships for 1',1'-dimethylalkyl-Delta8-tetrahydrocannabinols. | 2003-04-03 |
|
| Ethanol effects on local cerebral glucose utilization in high-alcohol-drinking and low-alcohol-drinking rats. | 2003-01 |
|
| Biodegradation of MTBE and BTEX in an aerobic fluidized bed reactor. | 2003 |
|
| Urokinase, a constitutive component of the inflamed synovial fluid, induces arthritis. | 2003 |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: https://www.drugs.com/uk/pdf/leaflet/1049775.pdf
For the symptomatic relief of muscular pain and stiffness, including backache, sciatica, lumbago, fibrositis, rheumatic pain.
Ralgex Freeze Spray contains Glycol Monosalicylate 10% w/w, Methoxymethane 14.41% w/w and Isopentane 67.77% w/w.
How to use this spray
Adults, the elderly and children 5 years and over:
• Shake well before use. in with the arrow pointing to the site of pain
• Hold the can about 6 inches from the skin.
• Press button to spray 2‐3 short bursts.
• This may be repeated up to 4 times daily
Route of Administration:
Topical
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:16:00 GMT 2025
by
admin
on
Mon Mar 31 19:16:00 GMT 2025
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| Record UNII |
ZH67814I0O
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| Record Status |
Validated (UNII)
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NCI_THESAURUS |
C718
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30362
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C067038
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C63387
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ZH67814I0O
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ISOPENTANE
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SUB77785
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ACTIVE MOIETY |