Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 13:58:58 GMT 2023
by
admin
on
Sat Dec 16 13:58:58 GMT 2023
|
| Protein Type | RECEPTOR |
| Protein Sub Type | Other |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
ZFQG2GI3F2
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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301156-53-6
Created by
admin on Sat Dec 16 13:58:59 GMT 2023 , Edited by admin on Sat Dec 16 13:58:59 GMT 2023
|
PRIMARY | |||
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ZFQG2GI3F2
Created by
admin on Sat Dec 16 13:58:59 GMT 2023 , Edited by admin on Sat Dec 16 13:58:59 GMT 2023
|
PRIMARY | |||
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Q06124
Created by
admin on Sat Dec 16 13:58:59 GMT 2023 , Edited by admin on Sat Dec 16 13:58:59 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
ALLOSTERIC INHIBITOR->TARGET |
IN-VITRO
IC50
|
||
|
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ACTIVATOR->OFF TARGET |
Kd
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
ALLOSTERIC INHIBITOR
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INHIBITOR -> TARGET |
Greatly reduced effect in the SHP2 E76K or T253M/Q257L mutants.
ALLOSTERIC
IC50
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||
|
INHIBITOR -> TARGET |
|
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
|