AMILORIDE-SENSITIVE SODIUM CHANNEL

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 00:31:05 GMT 2025` Edited by `admin` on `Wed Apr 02 00:31:05 GMT 2025`
Protein Sub Type	ION CHANNEL
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	ZEX6X6B5QP
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ENAC

Preferred Name

English

AMILORIDE-SENSITIVE SODIUM CHANNEL

Common Name

English

Epithelial Sodium Channel–

Common Name

English

Epithelial Na(+) channel

Common Name

English

Nonvoltage-gated sodium channel 1

Common Name

English

Code System Code Type Description

UNIPROT

P51168

Created by admin on Wed Apr 02 00:31:05 GMT 2025 , Edited by admin on Wed Apr 02 00:31:05 GMT 2025

PRIMARY

UNIPROT

P37088

Created by admin on Wed Apr 02 00:31:05 GMT 2025 , Edited by admin on Wed Apr 02 00:31:05 GMT 2025

PRIMARY

UNIPROT

P51170

Created by admin on Wed Apr 02 00:31:05 GMT 2025 , Edited by admin on Wed Apr 02 00:31:05 GMT 2025

PRIMARY

FDA UNII

ZEX6X6B5QP

Created by admin on Wed Apr 02 00:31:05 GMT 2025 , Edited by admin on Wed Apr 02 00:31:05 GMT 2025

PRIMARY

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	2_260
N	3_209
N	3_497

Related Record Type Details


					A6KAB92LQ7

SPX-101

INHIBITOR -> TARGET

Comments:

Binds selectively to ENaC and promotes internalization of the a-, b-, and g-subunits. Removing ENaC from the membrane with SPX-101 causes a significant decrease in amiloride-sensitive current.

Qualification:

EC50

Amount: