Amrecibart

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 19:43:13 GMT 2025` Edited by `admin` on `Wed Apr 02 19:43:13 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4\|KAPPA
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	ZDR9VW2WMN
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Amrecibart

Official Name

English

Immunoglobulin G4 [231-proline], anti-(human blood-coagulation factor XI) (human monoclonal REGN9933 ?4-chain), disulfide with human monoclonal REGN9933 ?-chain, dimer

Preferred Name

English

amrecibart [INN]

Common Name

English

Code System Code Type Description

CAS

3008610-20-3

Created by admin on Wed Apr 02 19:43:13 GMT 2025 , Edited by admin on Wed Apr 02 19:43:13 GMT 2025

PRIMARY

FDA UNII

ZDR9VW2WMN

Created by admin on Wed Apr 02 19:43:13 GMT 2025 , Edited by admin on Wed Apr 02 19:43:13 GMT 2025

PRIMARY

INN

13412

Created by admin on Wed Apr 02 19:43:13 GMT 2025 , Edited by admin on Wed Apr 02 19:43:13 GMT 2025

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From	To
1_22	1_96
2_22	2_96
2_137	4_215
2_150	2_206
2_264	2_324
1_137	3_215
2_370	2_428
3_23	3_88
3_135	3_195
4_23	4_88
4_135	4_195
1_150	1_206
1_229	2_229
1_232	2_232
1_264	1_324
1_370	1_428

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_300
N	2_300

Related Record Type Details


					ZDR9VW2WMN

Amrecibart

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_450] [2_450]	C-TERMINUS		Amount:	LYSINE	K3Z4F929H6
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS	E	Amount:	PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL